Soluble polymer-supported convergent parallel library synthesis

Literature Information

Publication Date 2003-01-27
DOI 10.1039/B210696E
Impact Factor 6.222
Authors

Jung-Mo Ahn, Paul Wentworth Jr., Kim D. Janda


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Abstract

Soluble polymer-supported convergent synthesis has for the first time been successfully exploited for parallel library synthesis; sub-libraries of tripeptide iodoarenes and arylboronic acids reacted smoothly in a multipolymer PdII-catalyzed Suzuki coupling reaction to generate a library of bisaryl-linked hexapeptides.

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