Preparation of a unique glucan with large intervals in molecular weight distribution. Controlled ring-opening polymerization of O-permethylcyclodextrin

Literature Information

Publication Date 2003-01-20
DOI 10.1039/B210122J
Impact Factor 3.876
Authors

Masato Suzuki, Tomofumi Shimazaki


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Abstract

O-Permethylated cyclodextrins (MeCDs) were found to be polymerizable with the initiator–activator system of HI–I2 or HI–ZnX2, undergoing ring-cleavage to give linear 1→4-glucan. Among several conditions investigated, HI–ZnCl2 in CH2Cl2 at 0 °C proved most effective to control this cationic ring-opening polymerization (CROP). The MALDI-TOF-MS spectrum revealed that the molecular weight distribution of the glucan obtained from γ-MeCD uniquely consisted of large, regular intervals, each of which were identical to the molecular weight of γ-MeCD (1634).

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Organic & Biomolecular Chemistry

Organic & Biomolecular Chemistry
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Organic & Biomolecular Chemistry (OBC) publishes original and high impact research and reviews in organic chemistry. We welcome research that shows new or significantly improved protocols or methodologies in total synthesis, synthetic methodology or physical and theoretical organic chemistry as well as research that shows a significant advance in the organic chemistry or molecular design aspects of chemical biology, catalysis, supramolecular and macromolecular chemistry, theoretical chemistry, mechanism-oriented physical organic chemistry, medicinal chemistry or natural products. Articles published in the journal should report new work which makes a highly-significant impact in the field. Routine and incremental work is generally not suitable for publication in the journal. More details about key areas of our scope are below. In all cases authors should include in their article clear rationale for why their research has been carried out.

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