Spin trapping of superoxide in the presence of β-cyclodextrins

Literature Information

Publication Date 2002-11-13
DOI 10.1039/B209787G
Impact Factor 6.222
Authors

Hakim Karoui, Antal Rockenbauer, Sylvie Pietri, Paul Tordo


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Abstract

The trapping of superoxide anion with DMPO and DEPMPO has been carried out in the presence of a methylated β-cyclodextrin, Me-β-CD; inclusion of the spin adducts in the cavity of Me-β-CD resulted in a seven-fold increase of their half-life (t1/2 = 96 min for DEPMPO-superoxide spin adduct) and in their protection towards glutathione peroxidase (Gpx) and also ascorbate anion in the case of DEPMPO.

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