Role of functional groups in determining interactions in ternary aqueous solutions of enantiomeric α-amino acids: a calorimetric study at 298 K
Literature Information
Cross-homochiral and cross-heterochiral enthalpic interaction coefficients were determined at 298 K by measuring the enthalpies of dilution in water of ternary solutions containing two different α-amino acids of the same or different chirality: phenylalanine, glutamine, leucine, asparagine, cysteine, methionine, citrulline, tryptophan. The interaction of these amino acids with small molecules such as glycine, formamide and urea was also studied in the attempt to separate the contribution of the functional groups to the overall interaction. The data are discussed in terms of the preferential configuration model. It is found that the interaction between the hydrophilic groups, the zwitterions, which is thermochemically attractive, mostly determines the values of the coefficients. In some cases, differences were found between the values of the cross-homochiral and cross-heterochiral coefficients: namely, the variation of the interactions between the side chains significantly influences the energetics of the interaction.
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Physical Chemistry Chemical Physics (PCCP) is an international journal co-owned by 19 physical chemistry and physics societies from around the world. This journal publishes original, cutting-edge research in physical chemistry, chemical physics and biophysical chemistry. To be suitable for publication in PCCP, articles must include significant innovation and/or insight into physical chemistry; this is the most important criterion that reviewers and Editors will judge against when evaluating submissions. The journal has a broad scope and welcomes contributions spanning experiment, theory, computation and data science. Topical coverage includes spectroscopy, dynamics, kinetics, statistical mechanics, thermodynamics, electrochemistry, catalysis, surface science, quantum mechanics, quantum computing and machine learning. Interdisciplinary research areas such as polymers and soft matter, materials, nanoscience, energy, surfaces/interfaces, and biophysical chemistry are welcomed if they demonstrate significant innovation and/or insight into physical chemistry. Joined experimental/theoretical studies are particularly appreciated when complementary and based on up-to-date approaches.










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