1,4-Dioxaspiro[4.5]decan-8-amine

Basic Information

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CAS Number

97096-16-7

Molecular Formula

C8H15NO2

Molecular Weight

157.21 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Boiling Point

247℃ at 760 mmHg

Density

1.11

Flash Point

111.1℃

Refractive Index

1.509

SMILES

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C1CC2(CCC1N)OCCO2

InChI

InChI=1S/C8H15NO2/c9-7-1-3-8(4-2-7)10-5-6-11-8/h7H,1-6,9H2

InChIKey

KDAFVGCPLFJMHY-UHFFFAOYSA-N

LogP

0.6307999999999998

Topological Polar Surface Area

44.480000000000004 Å²

Hydrogen Bond Donor/Acceptor

2 / 3

Complexity

133

Synonyms & References

English

1,4-Dioxaspiro[4.5]decan-8-amine
1,4-DIOXA-SPIRO[4·5]DEC-8-YLAMINE,
1,4-amino cyclohexanone ethylene ketal
1,4-Dioxaspiro[4.5]dec-8-ylamine
1,4-Dioxaspiro<4.5>dec-8-ylamin
4-aminocyclohexanone ethylene ketal
8-Amino-1,4-dioxaspiro[4,5]decane
1,4-Dioxa-spiro[4.5]dec-8-ylamine
KDAFVGCPLFJMHY-UHFFFAOYSA-N
KM3438
SBB087219
1,4-Dioxaspiro[4.5]decane-8-amine
TRA0086786
AB18565
SY017242
(1,4-dioxa-spiro[4.5]dec-8-yl)amine
(1,4-Dioxa-spiro[4.5]dec-8-yl)-amine
V9885
CS
(1,4-Dioxaspiro[4.5]dec-8-yl)amine
(1,4-Dioxaspiro[4.5]decan-8-yl)amine
1,4-dioxaspiro[4.5]decan-8-amine
1,4-dioxaspiro[4.5]dec-8-ylamine
CS-0040044
1,4-Dioxa-spiro[4 middot 5]dec-8-ylamine
1,4-Dioxa-spiro[4.5]dec-8-ylamine, AldrichCPR
Z239627340
8-Amino-1 pound not4-dioxaspiro[4 pound not5]decane
8-AMINO-1,4-DIOXASPIRO[4,5]DECANE
DTXSID60562412
AKOS000142555

MDL Number

MFCD04114556

Customs Code

2932999099

FAQ

What are the physical and chemical properties of 1,4-Dioxaspiro[4.5]decan-8-amine (CAS: 97096-16-7)?

1,4-Dioxaspiro[4.5]decan-8-amine, also known as 1,4-dioxaspirodecane-8-amine, is a white crystalline solid with a molecular weight of approximately 220.29 g/mol. It has a solubility of about 1.54 g/100 mL in water. The compound is moderately reactive with acidic and basic solutions. It does not readily undergo hydrolysis but can react with certain nucleophiles and electrophiles.

How is 1,4-Dioxaspiro[4.5]decan-8-amine (CAS: 97096-16-7) typically synthesized?

1,4-Dioxaspiro[4.5]decan-8-amine can be synthesized through the amidation of 1,4-dioxaspirodecane with an appropriate amine under basic conditions. Commonly, this involves stirring the reactants in a solvent such as dimethylformamide (DMF) with a base like sodium hydride, followed by the addition of an excess of the amine. The reaction is typically carried out at room temperature and yields a high purity product with good selectivity and yield.

What industries use 1,4-Dioxaspiro[4.5]decan-8-amine (CAS: 97096-16-7)?

1,4-Dioxaspiro[4.5]decan-8-amine finds application in the pharmaceutical industry as a precursor for drug synthesis. It is also used in the polymer industry for the development of certain types of polymers and in the sensor industry for its ability to interact with specific molecules. Additionally, it has applications in the semiconductor industry, particularly in the fabrication of organic semiconductor materials.

What precautions should be taken when handling 1,4-Dioxaspiro[4.5]decan-8-amine (CAS: 97096-16-7)?

When handling 1,4-Dioxaspiro[4.5]decan-8-amine, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be stored in a cool, dry place away from direct sunlight and heat sources. In case of a spill, the area should be immediately flushed with water, and the material should be collected using appropriate spill cleanup materials. Always refer to the Safety Data Sheet (SDS) for detailed procedures and emergency response guidelines.