Labetalone hydrochloride

Basic Information

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CAS Number

96441-14-4

Molecular Formula

C19H23ClN2O3

Molecular Weight

362.86 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ketones

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

217-220°C

SMILES

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CC(CCC1=CC=CC=C1)NCC(=O)C2=CC(=C(C=C2)O)C(=O)N.Cl

InChI

InChI=1S/C19H22N2O3.ClH/c1-13(7-8-14-5-3-2-4-6-14)21-12-18(23)15-9-10-17(22)16(11-15)19(20)24;/h2-6,9-11,13,21-22H,7-8,12H2,1H3,(H2,20,24);1H

InChIKey

DJHFVUYXWAEVRA-UHFFFAOYSA-N

LogP

2.706500000000001

Topological Polar Surface Area

92.42 Å²

Hydrogen Bond Donor/Acceptor

4 / 5

Complexity

421

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

Labetalone hydrochloride
BENZOYLAMIDE
BENZOIC AMIDE
benzenecarbonamide
2-Hydroxy-5-(2-(4-phenylbutan-2-ylamino)acetyl)benzamide hydrochloride
2-HYDROXY-5-[[(1-METHYL-3-PHENYLPROPYL)AMINO]ACETYL]BENZAMIDE HCl
2-hydroxy-5-[2-(4-phenylbutan-2-ylamino)acetyl]benzamide,hydrochloride
Labetalone HCl
Benzamide, 2-hydroxy-5-[[(1-methyl-3-phenylpropyl)amino]acetyl]-, monohydrochloride (9CI)
Labetalol EP ImpurityG
Labetalol EP ImpurityF
2-Hydroxy-5-((4-phenylbutan-2-yl)glycyl)benzamide
hydrochloride (1:1)
2-hydroxy-5-{2-[(4-phenylbutan-2-yl)amino]acetyl}benzamide hydrochloride
DB-091559
96441-14-4
Benzamide, 2-hydroxy-5-[[(1-methyl-3-phenylpropyl)amino]acetyl]-,monohydrochloride
CS-0099454
2-Hydroxy-5-(((4-phenylbutan-2-yl)amino)acetyl)benzamide hydrochloride
s5088
rac-Keto Labetalol Hydrochloride
AS-12814
2-Hydroxy-5-[N-(4-phenylbutan-2-yl)glycyl]benzamide--hydrogen chloride (1/1)
LabetaloneHCl
SB83677
DTXSID60679731
HY-128379
BCP12787
Labetalone; 2-?Hydroxy-?5-?[2-?[(1-?methyl-?3-?phenylpropyl)?amino]?acetyl]benzamide Hydrochloride; 2-Hydroxy-5-[[(1-methyl-3-phenylpropyl)amino]acetyl]benzamide Monohydrochloride; Labetalone Hydrochloride
E83951
EC 700-288-4

MDL Number

MFCD08460398

FAQ

What is Labetalone hydrochloride (CAS: 96441-14-4)?

Labetalone hydrochloride is a drug used in the treatment of hypertension and certain heart conditions. It is a beta-blocker and alpha-1-adrenergic antagonist with a hydrochloride salt form. It has the chemical formula C22H28ClN2O2·HCl.

What are the main uses of Labetalone hydrochloride (CAS: 96441-14-4)?

Labetalone hydrochloride is primarily used for the treatment of hypertension and as an adjunct in the treatment of angina pectoris. It is also used in certain clinical settings for its vasodilatory properties.

Is Labetalone hydrochloride (CAS: 96441-14-4) safe?

Labetalone hydrochloride is generally considered safe when used as directed. However, it can cause side effects such as hypotension, bradycardia, and exacerbation of angina. Patients should follow medical advice and take necessary precautions to avoid adverse reactions.

How should Labetalone hydrochloride (CAS: 96441-14-4) be stored?

Labetalone hydrochloride should be stored at room temperature (15-30°C) in a tightly closed container, protected from light. It should be kept away from moisture and heat to maintain its stability. Do not freeze the medication.