2'-Deoxyadenosine

Basic Information

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CAS Number

958-09-8

Molecular Formula

C10H13N5O3

Molecular Weight

251.25 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Melting Point

188.0 to 192.0 deg-C

Boiling Point

394.4°C (rough estimate)

Density

1.2938 (rough estimate)

Water Solubility

Soluble in water and caustic soda.

Flash Point

627.2 °C at 760 mmHg

Refractive Index

1.7610 (estimate)

Specific Rotation

-25° (c=0.5 in water)

SMILES

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O[C@@H]1[C@@H](CO)O[C@@H](N2C=NC3=C(N)N=CN=C23)C1

InChI

InChI=1S/C10H13N5O3/c11-9-8-10(13-3-12-9)15(4-14-8)7-1-5(17)6(2-16)18-7/h3-7,16-17H,1-2H2,(H2,11,12,13)/t5-,6+,7+/m0/s1

InChIKey

OLXZPDWKRNYJJZ-RRKCRQDMSA-N

LogP

-0.9508000000000005

Topological Polar Surface Area

119.30999999999999 Å²

Hydrogen Bond Donor/Acceptor

4 / 8

Complexity

307

Safety Information

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GHS Hazard Pictograms

H301

Hazard Statement

H301 Toxic if swallowed
Acute toxicity, oral

Hazard Class

Class 6.1 Class 6.1

Synonyms & References

English

2'-deoxyadenosine
Deoxyadenosine
2`-Deoxyadenosine
2'-Deoxyadenosine Anhydrous
2'-DEOXY-D-ADENOSINE
adeninedeoxyribose
Adenosine,2'-deoxy
Adenyldeoxyriboside
DEOXYADENOSINE-2'
DESOXYADENOSINE
Adenine deoxyribonucleoside
Adenine deoxyribose
(2R,3S,5R)-5-(6-amino-9H-purin-9-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol
Adenine deoxy nucleoside
2-Deoxyadenosine
2'-Deoxyformycin A
ADENOSINE, 2'-DEOXY-
(2R,3S,5R)-5-(6-amino-9H-purin-9-yl)-2-(hydroxymethyl)oxolan-3-ol
Adenine deoxyriboside
beta-D-ery
2′-Deoxyadenosine (ACI)
167: PN: US20040053876 SEQID: 167 unclaimed DNA
78: PN: WO2022263569 PAGE: 208 claimed sequence
9-(2-Deoxy-β-D-erythro-pentofuranosyl)adenine
D
9: PN: WO2022247943 SEQID: 61 claimed sequence
9H-Purin-6-amine, 9-(2-deoxy-β-D-erythro-pentofuranosyl)-
9H-Purin-6-amine, 9-(2-deoxy-β-D-ribofuranosyl)-
dA
Desoxyadenosine
NQZ-035

MDL Number

MFCD00005754

Customs Code

2934999090

FAQ

What is 2'-Deoxyadenosine (CAS: 958-09-8)?

2'-Deoxyadenosine is a nucleoside composed of the sugar deoxyribose and the nucleobase adenine. Its chemical formula is C10H13N5O4. It is a key component in DNA and is used in various biochemical and pharmaceutical applications. The compound is known for its role in nucleic acid synthesis and has a molecular weight of approximately 267.23 g/mol.

What are the main uses of 2'-Deoxyadenosine (CAS: 958-09-8)?

2'-Deoxyadenosine is primarily used in research related to DNA and RNA synthesis, as well as in the development of antiviral and anticancer drugs. It serves as a building block in the production of nucleotides and is also employed in molecular biology techniques. Additionally, it has applications in the pharmaceutical industry for therapeutic purposes.

Is 2'-Deoxyadenosine (CAS: 958-09-8) safe?

2'-Deoxyadenosine is generally considered safe when handled properly, but it requires caution due to potential toxicity at high concentrations. It is classified as a hazardous substance under certain regulations, and appropriate protective measures such as gloves and ventilation should be used. Safety data sheets (SDS) should be consulted for detailed handling and exposure guidelines.

How should 2'-Deoxyadenosine (CAS: 958-09-8) be stored?

2'-Deoxyadenosine should be stored in a cool, dry, and dark place, ideally at 2-8°C. It is sensitive to moisture and light, so it must be kept in a sealed container and protected from humidity. Proper storage ensures its stability and prevents degradation, making it crucial for maintaining the compound's integrity and effectiveness.