5-Chloro-1H-pyrazolo[4,3-b]pyridine

Basic Information

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CAS Number

94220-45-8

Molecular Formula

C6H4ClN3

Molecular Weight

153.57 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Physical State

White to Yellow Solid

Boiling Point

323.8°C at 760 mmHg

Density

1.531

Flash Point

323.8 °C at 760 mmHg

Refractive Index

1.72

SMILES

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C1=CC(=NC2=C1NN=C2)Cl

InChI

InChI=1S/C6H4ClN3/c7-6-2-1-4-5(9-6)3-8-10-4/h1-3H,(H,8,10)

InChIKey

PYZUYYOYVZFJGX-UHFFFAOYSA-N

LogP

1.6112999999999993

Topological Polar Surface Area

41.57 Å²

Hydrogen Bond Donor/Acceptor

1 / 3

Complexity

130

Safety Information

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GHS Hazard Pictograms

H302

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

Synonyms & References

English

5-Chloro-1H-pyrazolo[4,3-b]pyridine
5-Chlor-1H-pyrazolo<4,3-b>pyridin
5-chloro-1(2)H-pyrazolo[4,3-b]pyridine
5-Chloro-1H-pyrazolo(4,3-b)pyridine
RW3802
1H-Pyrazolo[4,3-b]pyridine, 5-chloro-
5-Chloro-4-aza-1H-indazole
PYZUYYOYVZFJGX-UHFFFAOYSA-N
BCP07454
FCH850124
VP13574
PB21874
SY020606
OR301099
5-chloranyl-1H-pyrazolo[4,3-b]pyridine
AX8029922
ST1211261
AB0027786
4
5-Chloro-1H-pyrazolo[4,3-b]pyridine (ACI)
5-CHLORO-1H-PYRAZOLO[4,3-B]PYRIDINE
5-chloro-1H-pyrazolo[4,3-b]pyridine
94220-45-8
J-517253
DB-079825
DS-10864
MFCD05663984
CS-D0857
AC-28273
5-Chloro-2h-pyrazolo[4,3-b]pyridine
2931433-65-5

MDL Number

MFCD05663984

Customs Code

2933990090

FAQ

What regulatory guidelines apply to 5-Chloro-1H-pyrazolo[4,3-b]pyridine (CAS: 94220-45-8)?

5-Chloro-1H-pyrazolo[4,3-b]pyridine (CAS: 94220-45-8) falls under the hazard category of a reactive chemical with potential fire and explosion risks. It is regulated under the Globally Harmonized System (GHS) and requires classification as a flammable solid. In the European Union, it is subject to the REACH regulation, which may require authorization if it meets certain criteria. In the USA, the EPA and FDA have oversight responsibilities, with specific storage and handling requirements under the Resource Conservation and Recovery Act (RCRA).

Are there alternatives to 5-Chloro-1H-pyrazolo[4,3-b]pyridine in synthesis?

There are several alternatives to 5-Chloro-1H-pyrazolo[4,3-b]pyridine in synthesis, including 3-chloropyridine and 6-chloropyrazine. While not direct substitutes, these compounds can be used in similar synthetic pathways. Other alternatives focus on isomers or structural analogs like 5-bromo-1H-pyrazolo[4,3-b]pyridine, depending on the specific application and desired properties.

What is the market or research trend for 5-Chloro-1H-pyrazolo[4,3-b]pyridine (CAS: 94220-45-8)?

5-Chloro-1H-pyrazolo[4,3-b]pyridine (CAS: 94220-45-8) is increasingly being studied for its potential in drug development, particularly in anti-inflammatory and anticancer therapies. Market trends show growing interest in this compound due to its unique pharmacological properties. Research is also exploring its use in materials science for its reactive nature. Prices are expected to remain stable, with demand driven by emerging applications in both pharmaceutical and industrial sectors.

How should waste containing 5-Chloro-1H-pyrazolo[4,3-b]pyridine (CAS: 94220-45-8) be handled?

Waste containing 5-Chloro-1H-pyrazolo[4,3-b]pyridine (CAS: 94220-45-8) should be handled as a hazardous material. Collect it using appropriate containers and label them with the correct hazard symbols and chemical name. For disposal, consult local regulations, but generally, such wastes should be incinerated or treated by a professional hazardous waste management service. Ensure all safety precautions are taken during handling to prevent exposure and ensure compliance with environmental regulations.