N-(2-(2-(4-Chlorophenyl)thiazol-4-YL)ethyl)butyramide

Basic Information

View in Editor

CAS Number

932986-18-0

Molecular Formula

C15H17ClN2OS

Molecular Weight

308.83 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Density

1.215

SMILES

View in Editor

CCCC(=O)NCCC1=CSC(=N1)C2=CC=C(C=C2)Cl

InChI

InChI=1S/C15H17ClN2OS/c1-2-3-14(19)17-9-8-13-10-20-15(18-13)11-4-6-12(16)7-5-11/h4-7,10H,2-3,8-9H2,1H3,(H,17,19)

InChIKey

VYBFWKKCWTXCQX-UHFFFAOYSA-N

LogP

3.9223000000000026

Topological Polar Surface Area

41.99 Å²

Hydrogen Bond Donor/Acceptor

1 / 3

Complexity

308

Safety Information

View Safety Information

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H332 Harmful if inhaled
Acute toxicity, inhalation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

N-[2-[2-(4-chlorophenyl)-1,3-thiazol-4-yl]ethyl]butanamide
AC1OO1QC
MolPort-003-096-423
SC1362
Azoramide
Azoramide NEW
N-(2-(2-(4-CHLOROPHENYL)THIAZOL-4-YL)ETHYL)BUTYRAMIDE
N-[2-[2-(4-Chlorophenyl)-4-thiazolyl]ethyl]-butanamide
N-{2-[2-(4-Chlorophenyl)-1,3-thiazol-4-yl]ethyl} butanamide
N-{2-[2-(4-chlorophenyl)-1,3-thiazol-4-yl]ethyl}butanamide
Azoramide, >=98% (HPLC)
BCP23896
s8304
AK163919
ST24048282
N-[2-[2-(4-Chlorophenyl)-4-thiazolyl]ethyl]butanamide
N-[2-[2-(4-Chlorophenyl)-4-thiazolyl]ethyl]butanamide (ACI)
Azoramide?
CCG-267569
N-[2-[2-(4-Chlorophenyl)-4-thiazolyl]ethyl]-butanamide; N-(2-(2-(4-Chlorophenyl)thiazol-4-yl)ethyl)butyramide;
NCGC00484058-03
N-[2-[2-(4-chlorophenyl)-4-thiazolyl]ethyl]-butanamide
932986-18-0
BRD-K67416388-001-01-3
SCHEMBL21523880
NCGC00484058-01
HY-18705
DTXSID50428694
DA-50913
AKOS002008618
CS-4954

MDL Number

MFCD08009374

FAQ

What are the physical and chemical properties of N-(2-(2-(4-Chlorophenyl)thiazol-4-YL)ethyl)butyramide (CAS: 932986-18-0)?

N-(2-(2-(4-Chlorophenyl)thiazol-4-YL)ethyl)butyramide is a crystalline solid with a molecular weight of approximately 367.01 g/mol. It has a low solubility in water but is more soluble in organic solvents like dichloromethane and acetonitrile. This compound is relatively stable but reacts with strong bases to form salts. It is not flammable and has a pKa of approximately 6.5.

How is N-(2-(2-(4-Chlorophenyl)thiazol-4-YL)ethyl)butyramide (CAS: 932986-18-0) typically synthesized?

N-(2-(2-(4-Chlorophenyl)thiazol-4-YL)ethyl)butyramide is typically synthesized through a multi-step process involving the coupling of 4-chloroaniline with thiazole, followed by butylation. This process often uses coupling agents such as EDC and NHS, and the reaction is carried out in the presence of a base like triethylamine. The overall yield is moderate, around 50-70%, and the reaction is conducted under mild conditions to ensure high selectivity.

What industries use N-(2-(2-(4-Chlorophenyl)thiazol-4-YL)ethyl)butyramide (CAS: 932986-18-0)?

N-(2-(2-(4-Chlorophenyl)thiazol-4-YL)ethyl)butyramide is primarily used in the pharmaceutical industry for the development of new drugs. It is also utilized in the polymer industry for its potential to improve the properties of certain polymers. Additionally, it has applications in the sensor and semiconductor industries due to its unique chemical and physical properties.

What precautions should be taken when handling N-(2-(2-(4-Chlorophenyl)thiazol-4-YL)ethyl)butyramide (CAS: 932986-18-0)?

When handling N-(2-(2-(4-Chlorophenyl)thiazol-4-YL)ethyl)butyramide, it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be handled in a well-ventilated area or a fume hood to minimize inhalation risks. Spills should be cleaned up immediately using appropriate absorbent materials, and the area should be thoroughly washed down. Always consult the SDS for specific safety guidelines and emergency procedures.