Sulfo-SMCC | CAS No. 92921-24-9

Sulfo-SMCC

Basic Information

View in Editor

CAS Number

92921-24-9

Molecular Formula

C16H18N2NaO9S

Molecular Weight

437.38 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Surfactants Anionic Surfactants

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Melting Point

>270°C (dec.)

Water Solubility

Soluble in water (2.5 mg/ml) and dimethyl formamide.

Solubility

H2O: soluble2.5mg/mL

SMILES

View in Editor

C1CC(CCC1CN2C(=O)C=CC2=O)C(=O)ON3C(=O)CC(C3=O)S(=O)(=O)[O-].[Na+]

InChI

1S/C16H18N2O9S.Na/c19-12-5-6-13(20)17(12)8-9-1-3-10(4-2-9)16(23)27-18-14(21)7-11(15(18)22)28(24,25)26;/h5-6,9-11H,1-4,7-8H2,(H,24,25,26);

InChIKey

VRMVBDHSLMDJAD-UHFFFAOYSA-N

LogP

-0.19470

Complexity

853

Safety Information

View Safety Information

GHS Hazard Pictograms

H315

H319

H335

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Stability

Moisture Sensitive

Synonyms & References

English

Sodium 1-((4-((2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)methyl)cyclohexanecarbonyl)oxy)-2,5-dioxopyrrolidine-3-sulfonate
4-(N-Maleimidomethyl)cyclohexane-1-carboxylic acid 3-sulfo-N-hydroxysuccinimide ester
3-Sulfo-N-succinimidyl 4-(N-Maleimidomethyl)cyclohexane-1-carboxylate Sodium Salt
3-Sulfo-N-succinimidyl 4-(maleimidomethyl)cyclohexane-1-carboxylate sodium salt
4-(N-Maleimidomethyl)cyclohexane-1-carboxylic acid 3-sulfo-N-hydroxysuccinimide ester sodium salt
sodium,1-[4-[(2,5-dioxopyrrol-1-yl)methyl]cyclohexanecarbonyl]oxy-2,5-dioxopyrrolidine-3-sulfonate
Sulfo-N-Succinimidyl
SULFO-N-SUCCINIMIDYL 4-(MALEIMIDOMETHYL)CYCLOHEXANE-1 -CARBOXYLATE , SODIUM SALT
Sulfo-SMCC
Sulfo-SMCC (sodium)
Sulphosuccinimidyl-4-(N-maleimidomethyl)cyclohexane-1-carboxylate sodium salt
Sulfo-SMCC Sodium Salt
4-[(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)methyl]-Cyclohexanecarboxylic acid 2,5-dioxo-3-sulfo-1-pyrrolidinyl ester sodium salt (1:1)
Sulfo-SMCC sodium
Sulfo-SMCC Crosslinker
Sulfo-trans-SMCC
Sulfo-N-succinimidyl 4-(maleimidomethyl)cyclohexane-1-carboxylate sodium salt
C16H17N2NaO9S
VUFNRPJNRFOTGK-UHFFFAOYSA-M
Sulphosuccinimidyl-4-(N-maleimidomethyl)cyclohexane-1-carboxy
3-Pyrrolidinesulfonic acid, 1-[[[4-[(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)methyl]cyclohexyl]carbonyl]oxy]-2,5-dioxo-, sodium salt (9CI)
Sulfosuccinimidyl 4-(N-maleimidomethyl)cyclohexane-1-carboxylate
Sulfo-N-Succinimidyl 4-(Maleimidomethyl)cyclohexane-1-carboxylate, Sodium Salt, 90%
PD063671
SB19635
92921-24-9
HY-D0975
H10470
HH32D7TN36
AKOS022186734
trans-Sodium 1-((4-((2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)methyl)cyclohexane-1-carbonyl)oxy)-2,5-dioxopyrrolidine-3-sulfonate

MDL Number

MFCD00054978

FAQ

What are the physical and chemical properties of Sulfo-SMCC (CAS: 92921-24-9)?

Sulfo-SMCC (CAS: 92921-24-9) is a water-soluble compound. It has a molecular weight of approximately 436.31 g/mol. Sulfo-SMCC is soluble in water and ethanol. It is used as a cross-linker in protein conjugation. The compound is reactive towards thiol groups, allowing for efficient coupling reactions.

How is Sulfo-SMCC (CAS: 92921-24-9) typically synthesized?

Sulfo-SMCC (CAS: 92921-24-9) is typically synthesized by coupling maleimide and N-sulfosuccinimidyl 4-(p-azidophenyl)-butyrate. The synthesis involves the use of a carbodiimide as a coupling agent. The reaction is carried out in the presence of a catalyst to ensure high selectivity and yield.

What industries use Sulfo-SMCC (CAS: 92921-24-9)?

Sulfo-SMCC (CAS: 92921-24-9) is widely used in the pharmaceutical industry for protein conjugation and in biotechnology for immobilization of enzymes and antibodies. It is also used in the polymer industry for the modification of polymer surfaces. Additionally, it is employed in sensor technology for the development of biosensors and in semiconductor manufacturing for surface functionalization.

What precautions should be taken when handling Sulfo-SMCC (CAS: 92921-24-9)?

When handling Sulfo-SMCC (CAS: 92921-24-9), it is important to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a fume hood to minimize inhalation risks. Spills should be cleaned up immediately with care to avoid skin contact. Always refer to the safety data sheet (SDS) for detailed handling and safety information.