6-Bromo-1-(chloromethyl)-2-methoxynaphthalene

Basic Information

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CAS Number

92643-16-8

Molecular Formula

C12H10BrClO

Molecular Weight

285.57 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

144 °C

Boiling Point

379.5°Cat760mmHg

Density

1.491

Flash Point

183.3°C

Refractive Index

1.631

SMILES

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COC1=C(C2=C(C=C1)C=C(C=C2)Br)CCl

InChI

InChI=1S/C12H10BrClO/c1-15-12-5-2-8-6-9(13)3-4-10(8)11(12)7-14/h2-6H,7H2,1H3

InChIKey

BWIOURVJVDKDOC-UHFFFAOYSA-N

LogP

4.349700000000002

Topological Polar Surface Area

9.23 Å²

Hydrogen Bond Donor/Acceptor

0 / 1

Complexity

212

Safety Information

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Hazard Statement

Synonyms & References

English

AS-53732
6-bromo-1-chloromethyl-2-methoxy-naphthalene
IFLab1_003887
6-Bromo-1-chloromethyl-2-methoxynaphthalene
BWIOURVJVDKDOC-UHFFFAOYSA-N
92643-16-8
EN300-236140
MFCD01764689
A860008
FT-0620962
SCHEMBL3831940
HMS1423A15
Naphthalene, 6-bromo-1-(chloromethyl)-2-methoxy-
F0848-0243
6-bromo-1-(chloromethyl)-2-methoxynaphthalene
6-bromo-1-chloromethyl-2-methoxy-naphtha-lene
P17005
AKOS000267970
DTXSID00353169
Naphthalene,6-bromo-1-(chloromethyl)-2-methoxy-
6-Bromo-1-(chloromethyl)-2-methoxynaphthalene
(6-Brom-1-chlormethyl-[2]naphthyl)-methyl-aether
(6-bromo-1-chloromethyl-[2]naphthyl)-methyl ether
6-Brom-2-methoxy-1-chlormethyl-naphthalin

MDL Number

MFCD01764689

FAQ

What are the physical and chemical properties of 6-Bromo-1-(chloromethyl)-2-methoxynaphthalene (CAS: 92643-16-8)?

6-Bromo-1-(chloromethyl)-2-methoxynaphthalene (CAS: 92643-16-8) is a solid at room temperature, with a crystalline form and a molecular weight of approximately 289.03 g/mol. It has low solubility in water but is more soluble in organic solvents like dichloromethane and ethanol. This compound is less reactive towards common nucleophiles but can undergo substitution reactions under appropriate conditions. It is used in organic synthesis and pharmaceuticals.

How is 6-Bromo-1-(chloromethyl)-2-methoxynaphthalene (CAS: 92643-16-8) typically synthesized?

6-Bromo-1-(chloromethyl)-2-methoxynaphthalene (CAS: 92643-16-8) is typically synthesized via a multi-step process involving the bromination of 1-(chloromethyl)-2-methoxynaphthalene followed by selective methylation. This synthesis requires the use of Lewis acids and halogenating agents, providing high yield and selectivity. The reaction is carried out under anhydrous conditions to prevent side reactions.

What industries use 6-Bromo-1-(chloromethyl)-2-methoxynaphthalene (CAS: 92643-16-8)?

6-Bromo-1-(chloromethyl)-2-methoxynaphthalene (CAS: 92643-16-8) is used in various industries, including pharmaceuticals, where it serves as an intermediate in the synthesis of medicinally active compounds. It is also utilized in the production of certain polymers and as a reagent in analytical chemistry for developing sensors and semiconductors.

What precautions should be taken when handling 6-Bromo-1-(chloromethyl)-2-methoxynaphthalene (CAS: 92643-16-8)?

When handling 6-Bromo-1-(chloromethyl)-2-methoxynaphthalene (CAS: 92643-16-8), appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat should be worn. Work should be performed in a well-ventilated area or fume hood to avoid inhalation. Spills should be cleaned up using appropriate absorbent materials, and the area should be properly decontaminated. Always refer to the Safety Data Sheet (SDS) for detailed precautions and emergency procedures.