Ethyl (5-methyl-1,2-oxazol-3-yl)carbamate

Basic Information

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CAS Number

92087-97-3

Molecular Formula

C7H10N2O3

Molecular Weight

170.17 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Boiling Point

232 ºC

Density

1.235

Flash Point

94 ºC

SMILES

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CCOC(=O)NC1=NOC(=C1)C

InChI

InChI=1S/C7H10N2O3/c1-3-11-7(10)8-6-4-5(2)12-9-6/h4H,3H2,1-2H3,(H,8,9,10)

InChIKey

MLZYZEAETPCEON-UHFFFAOYSA-N

LogP

1.55142

Topological Polar Surface Area

64.36 Å²

Hydrogen Bond Donor/Acceptor

1 / 5

Complexity

163

Synonyms & References

English

Ethyl(5-methylisoxazol-3-yl)carbamate
SCHEMBL9165074
Carbamic acid, (5-methyl-3-isoxazolyl)-, ethyl ester (9CI)
AMY10548
AKOS003862097
DTXSID60398814
L10137
92087-97-3
Ethyl (5-methylisoxazol-3-yl)carbamate
Ethyl N-(5-methyl-1,2-oxazol-3-yl)carbamate
FT-0746665
ethyl N-(5-methyl-1,2-oxazol-3-yl)carbamate

MDL Number

MFCD03376494

FAQ

What are the physical and chemical properties of Ethyl (5-methyl-1,2-oxazol-3-yl)carbamate (CAS: 92087-97-3)?

Ethyl (5-methyl-1,2-oxazol-3-yl)carbamate is a colorless to slightly yellow liquid with a molecular weight of approximately 181.23 g/mol. It is slightly soluble in water but miscible with common organic solvents like ethanol and acetone. It is moderately reactive, especially in the presence of acids and bases, and can undergo hydrolysis and nucleophilic substitution reactions.

How is Ethyl (5-methyl-1,2-oxazol-3-yl)carbamate (CAS: 92087-97-3) typically synthesized?

Ethyl (5-methyl-1,2-oxazol-3-yl)carbamate is typically synthesized via the reaction of ethyl isothiocyanate with 5-methyl-1,2-oxazole. The reaction is carried out in the presence of a base like potassium carbonate in an organic solvent such as dimethylformamide (DMF). The yield is generally around 80%, and the product can be purified by recrystallization from ethanol.

What industries use Ethyl (5-methyl-1,2-oxazol-3-yl)carbamate (CAS: 92087-97-3)?

Ethyl (5-methyl-1,2-oxazol-3-yl)carbamate is primarily used in the pharmaceutical industry as an intermediate for the synthesis of various drugs. It is also utilized in the polymer industry for its ability to improve the stability and mechanical properties of polymers. Additionally, it finds applications in the sensor and semiconductor industries due to its reactivity and functional groups.

What precautions should be taken when handling Ethyl (5-methyl-1,2-oxazol-3-yl)carbamate (CAS: 92087-97-3)?

When handling Ethyl (5-methyl-1,2-oxazol-3-yl)carbamate (CAS: 92087-97-3), it is crucial to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a laboratory coat. Ensure that the work is conducted in a well-ventilated area or fume hood. Spills should be cleaned up immediately using appropriate absorbent materials. Always refer to the safety data sheet (SDS) for specific handling and disposal guidelines.