Desfluoro bicalutamide

Basic Information

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CAS Number

90357-05-4

Molecular Formula

C18H15F3N2O4S

Molecular Weight

17.03 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Nitriles

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

175-178 ºC (ethyl acetate hexane )

Density

1.48±0.1 g/cm3 (20 ºC 760 Torr),

Solubility

Insuluble (2.5E-3 g/L) (25 ºC),

SMILES

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CC(CS(=O)(=O)C1=CC=CC=C1)(C(=O)NC2=CC(=C(C=C2)C#N)C(F)(F)F)O

InChI

InChI=1S/C18H15F3N2O4S/c1-17(25,11-28(26,27)14-5-3-2-4-6-14)16(24)23-13-8-7-12(10-22)15(9-13)18(19,20)21/h2-9,25H,11H2,1H3,(H,23,24)

InChIKey

GDXNOJUTJPBYEC-UHFFFAOYSA-N

LogP

0.16199999999999998

Topological Polar Surface Area

35.0 Å²

Hydrogen Bond Donor/Acceptor

3 / 1

Complexity

719

Synonyms & References

English

Desfluoro Bicalutamide
3-(benzenesulfonyl)-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide
UNII-15LQ88H10F
N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methyl-3-(phenylsulfonyl)propanamide (ACI)
Propanamide, N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methyl-3-(phenylsulfonyl)-, (±)- (ZCI)
N-(4-Cyano-3-(trifluoromethyl)phenyl)-2-hydroxy-2-methyl-3-(phenylsulfonyl)propanamide
GDXNOJUTJPBYEC-UHFFFAOYSA-N
CS-0207771
3-(BENZENESULFONYL)-N-[4-CYANO-3-(TRIFLUOROMETHYL)PHENYL]-2-HYDROXY-2-METHYLPROPANAMIDE
(+/-)-N-[4-Cyano-3-(trifluoroMethyl)phenyl]-2-hydroxy-2-Methyl-3-(phenylsulfonyl)propanamide
Bicalutamide Impurity A
BICALUTAMIDE IMPURITY A [EP IMPURITY]
BS-24869
Q27251730
15LQ88H10F
MFCD24386587
BICALUTAMIDE IMPURITY A (EP IMPURITY)
90357-05-4
SCHEMBL4176657
Bicalutamide impurity A [EP]
(2RS)-N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methyl-3-(phenylsulfonyl)propanamide
N-[4-CYANO-3-(TRIFLUOROMETHYL)PHENYL]-2-HYDROXY-2-METHYL-3-(PHENYLSULFONYL)PROPANAMIDE
Propanamide, N-(4-cyano-3-(trifluoromethyl)phenyl)-2-hydroxy-2-methyl-3-(phenylsulfonyl)-, (+/-)-
AKOS025149217
CHEMBL173185
(+/-)-Desfluoro bicalutamide
Propanamide, N-(4-cyano-3-(trifluoromethyl)phenyl)-2-hydroxy-2-methyl-3-(phenylsulfonyl)-
(2RS)-N-(4-Cyano-3-(trifluoromethyl)phenyl)-2-hydroxy-2-methyl-3-(phenylsulfonyl)propanamide

MDL Number

MFCD24386587

FAQ

What is Desfluoro bicalutamide (CAS: 90357-05-4)?

Desfluoro bicalutamide is a pharmaceutical compound with the CAS number 90357-05-4. It is a derivative of bicalutamide, used in the treatment of prostate cancer by inhibiting the activity of androgen receptors.

What are the main uses of Desfluoro bicalutamide (CAS: 90357-05-4)?

Desfluoro bicalutamide is primarily used in the treatment of advanced or metastatic prostate cancer. It functions as an androgen receptor antagonist, helping to reduce the growth of cancer cells by blocking androgens' effects.

Is Desfluoro bicalutamide (CAS: 90357-05-4) safe?

Desfluoro bicalutamide is generally considered safe when used as directed by a healthcare provider. However, it may cause side effects such as hot flashes, nausea, and fatigue. Users should follow all safety guidelines and consult a doctor if experiencing adverse reactions.

How should Desfluoro bicalutamide (CAS: 90357-05-4) be stored?

Desfluoro bicalutamide should be stored in a tightly closed container, away from direct light and heat. Keep the medication in a cool, dry place, ideally between 15°C and 25°C (59°F to 77°F). Avoid exposure to moisture and maintain the original packaging to protect the integrity of the compound.