Tazobactam Diphenylmethyl Ester

Basic Information

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CAS Number

89789-07-1

Molecular Formula

C23H22N4O5S

Molecular Weight

466.52 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

SMILES

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CC1(C(N2C(S1(=O)=O)CC2=O)C(=O)OC(C3=CC=CC=C3)C4=CC=CC=C4)CN5C=CN=N5

InChI

InChI=1S/C23H22N4O5S/c1-23(15-26-13-12-24-25-26)21(27-18(28)14-19(27)33(23,30)31)22(29)32-20(16-8-4-2-5-9-16)17-10-6-3-7-11-17/h2-13,19-21H,14-15H2,1H3/t19-,21+,23+/m1/s1

InChIKey

PHGXFQIAGFMIHJ-NWSQWKLXSA-N

LogP

1.7250000000000003

Topological Polar Surface Area

111.46 Å²

Hydrogen Bond Donor/Acceptor

0 / 9

Complexity

847

Synonyms & References

English

Benzhydry 2β-triazolmethyl-2α-methyl-6,6-dihydropernicillanate-1,1-dioxide
Tazobactam Diphenylmethyl Ester
Benzhydry 2beta-triazolmethyl-2alpha-methyl-6,6-dihydropernicillanate-1,1-dioxide
1H-1,2,3-Triazole, 4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid deriv. (ZCI)
4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3-methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-, diphenylmethyl ester, 4,4-dioxide, [2S-(2α,3β,5α)]- (ZCI)
Tazobactam diphenylmethyl ester
benzhydryl (2S,3S,5R)-3-((1H-1,2,3-triazol-1-yl)methyl)-3-methyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate 4,4-dioxide
Benzhydryl (2S,3S,5R)-3-((1H-1,2,3-triazol-1-yl)methyl)-3-methyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate 4,4-dioxide
benzhydryl (2S,3S,5R)-3-methyl-4,4,7-trioxo-3-(triazol-1-ylmethyl)-4lambda6-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
G66131
DTXSID001100413
SCHEMBL1122108
EX-A1375
89789-07-1
1H-1,2,3-Triazole, 4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid deriv.
4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3-methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-, diphenylmethyl ester, 4,4-dioxide, (2S,3S,5R)-
(2S,3S,5R)-Diphenylmethyl 4,4-dioxo-3-(1,2,3-triazol-1-ylmethyl)-2-penicillanate

MDL Number

MFCD09751548

FAQ

What is Tazobactam Diphenylmethyl Ester (CAS: 89789-07-1)?

Tazobactam Diphenylmethyl Ester (CAS: 89789-07-1) is a beta-lactamase inhibitor used in combination with penicillins and cephalosporins to enhance their effectiveness against bacterial infections. It is a derivative of tazobactam, which helps to protect the parent antibiotic from degradation by beta-lactamase enzymes produced by some bacteria.

What are the main uses of Tazobactam Diphenylmethyl Ester (CAS: 89789-07-1)?

Tazobactam Diphenylmethyl Ester (CAS: 89789-07-1) is commonly used in the treatment of bacterial infections, particularly those caused by strains resistant to penicillins and cephalosporins. It is often combined with amoxicillin or piperacillin to form the antibiotic combination amoxicillin-clavulanate or piperacillin-tazobactam, which are used in clinical settings for infections such as respiratory, urinary, and skin infections.

Is Tazobactam Diphenylmethyl Ester (CAS: 89789-07-1) safe?

Tazobactam Diphenylmethyl Ester (CAS: 89789-07-1) is generally considered safe when used as directed under medical supervision. However, like all medications, it may cause side effects such as rash, gastrointestinal issues, and allergic reactions. Patients should follow prescribed dosages and consult a healthcare provider if any adverse effects occur.

How should Tazobactam Diphenylmethyl Ester (CAS: 89789-07-1) be stored?

Tazobactam Diphenylmethyl Ester (CAS: 89789-07-1) should be stored at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. It should be kept in a tightly closed container to protect it from light and air. Avoid storing it in damp or humid areas to prevent degradation.