2-(2-Benzofuranyl)-2-imidazoline hydrochloride

Basic Information

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CAS Number

89196-95-2

Molecular Formula

C11H11ClN2O

Molecular Weight

222.68 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Boiling Point

348.1°C at 760 mmHg

Flash Point

164.4°C

SMILES

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C1CN=C(N1)C2=CC3=CC=CC=C3O2.Cl

InChI

InChI=1S/C11H10N2O.ClH/c1-2-4-9-8(3-1)7-10(14-9)11-12-5-6-13-11;/h1-4,7H,5-6H2,(H,12,13);1H

InChIKey

RFNFFVDVGWOSNZ-UHFFFAOYSA-N

LogP

2.2043999999999997

Topological Polar Surface Area

37.53 Å²

Hydrogen Bond Donor/Acceptor

1 / 3

Complexity

252

Safety Information

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Hazard Statement

Synonyms & References

English

1H-Imidazole,2-(2-benzofuranyl)-4,5-dihydro-, hydrochloride (1:1)
2-(Benzofuran-2-yl)-2-imidazoline Hydrochloride
2-(1-benzofuran-2-yl)-4,5-dihydro-1H-imidazole,hydrochloride
2-(2-BENZOFURANYL)-2-IMIDAZOLINE HYDROCHLORIDE
2-BFI HYDROCHLORIDE
2 BFI
2-(2-benzofuranyl)-4,5-dihydro-1H-imidazole hydrochloride
RX 801077
2-(Benzofuran-2-yl)-2-imidazoline hydrochloride
1H-Imidazole, 2-(2-benzofuranyl)-4,5-dihydro-, monohydrochloride (9CI)
DTXSID80662766
2-(Benzofuran-2-yl)-4,5-dihydro-1H-imidazole hydrochloride
G78243
DA-69747
89196-95-2
TS-08264
PD022015
SCHEMBL4206556
2-BFI hydrochloride
2-BFI hydrochloride, >=98% (HPLC)
SR-01000597768-1
2-(2-benzo[b]furanyl)-2-imidazoline hydrochloride
2 BFI hydrochloride;RX801077 hydrochloride;RX-801077 hydrochloride
HY-100904
2-(1-Benzofuran-2-yl)-4,5-dihydro-1H-imidazole--hydrogen chloride (1/1)
RX 801077 (hydrochloride)
2-(1-benzofuran-2-yl)-4,5-dihydro-1H-imidazole;hydrochloride
2-(1-benzofuran-2-yl)-4,5-dihydro-1H-imidazole hydrochloride
GLXC-02851
SR-01000597768
CS-0020574

MDL Number

MFCD00672666

Customs Code

2934999090

FAQ

What regulatory guidelines apply to 2-(2-Benzofuranyl)-2-imidazoline hydrochloride (CAS: 89196-95-2)?

The compound 2-(2-Benzofuranyl)-2-imidazoline hydrochloride (CAS: 89196-95-2) must comply with various regulatory guidelines. Globally, it falls under the GHS (Globally Harmonized System of Classification and Labeling of Chemicals) for hazardous communication, including classification as a Category 1A sensitiser. For European markets, it is subject to REACH regulations, which require registration and notification to ECHA (European Chemicals Agency). In the United States, FDA and EPA regulations apply, particularly for any pharmaceutical or agricultural use, where specific handling and reporting requirements are enforced.

Are there alternatives to 2-(2-Benzofuranyl)-2-imidazoline hydrochloride (CAS: 89196-95-2) in synthesis?

There are several alternatives to 2-(2-Benzofuranyl)-2-imidazoline hydrochloride (CAS: 89196-95-2) in synthesis. Common alternatives include other imidazoline derivatives with different substituents, such as 2-(2-naphthyl)-2-imidazoline hydrochloride. Additionally, analogous compounds like benzimidazoles or other heterocyclic amines can serve as viable substitutes depending on the specific application. These alternatives offer similar functionalities but with variations in toxicity, stability, and reactivity.

What is the market or research trend for 2-(2-Benzofuranyl)-2-imidazoline hydrochloride (CAS: 89196-95-2)?

The market and research trends for 2-(2-Benzofuranyl)-2-imidazoline hydrochloride (CAS: 89196-95-2) are currently focused on its use as a sensitiser in pharmaceuticals and dermatological products. Recent studies are exploring its potential in allergy treatments and as a topical irritant. There is also growing interest in its application in controlled-release formulations and as a skin penetration enhancer. Market trends indicate increasing demand from the pharmaceutical industry, driven by the need for effective and safe sensitiser agents.

How should waste containing 2-(2-Benzofuranyl)-2-imidazoline hydrochloride (CAS: 89196-95-2) be handled?

Waste containing 2-(2-Benzofuranyl)-2-imidazoline hydrochloride (CAS: 89196-95-2) should be handled according to hazardous waste management guidelines. Collection should be done in compatible, leak-proof containers, and the waste should be labeled with proper hazardous waste labels. For disposal, it is advisable to incinerate the waste at an authorized facility or use professional waste disposal services. Environmental protection precautions include ensuring that no waste is discharged into the environment and that all handling and disposal activities comply with local, national, and international regulations. Protective equipment, such as gloves and goggles, must be worn during handling to prevent exposure to the sensitiser.