L-Tyrosylglycylglycyl-L-phenylalanyl-L-methionyl-N~5~-(diaminomethylidene)-L-ornithyl-N~5~-(diaminomethylidene)-L-ornithyl-L-valine | CAS No. 88866-92-6

L-Tyrosylglycylglycyl-L-phenylalanyl-L-methionyl-N~5~-(diaminomethylidene)-L-ornithyl-N~5~-(diaminomethylidene)-L-ornithyl-L-valine

Basic Information

CAS Number

88866-92-6

Molecular Formula

C44H68N14O10S

Molecular Weight

985.18 g/mol

AD

Basic Physical Properties

Density

1.42±0.1 g/cm3 (20 ºC 760 Torr),

CC(C)C(C(=O)O)NC(=O)C(CCCN=C(N)N)NC(=O)C(CCCN=C(N)N)NC(=O)C(CCSC)NC(=O)C(CC1=CC=CC=C1)NC(=O)CNC(=O)CNC(=O)C(CC2=CC=C(C=C2)O)N

InChI

InChI=1S/C44H68N14O10S/c1-25(2)36(42(67)68)58-40(65)31(12-8-19-51-44(48)49)56-38(63)30(11-7-18-50-43(46)47)55-39(64)32(17-20-69-3)57-41(66)33(22-26-9-5-4-6-10-26)54-35(61)24-52-34(60)23-53-37(62)29(45)21-27-13-15-28(59)16-14-27/h4-6,9-10,13-16,25,29-33,36,59H,7-8,11-12,17-24,45H2,1-3H3,(H,52,60)(H,53,62)(H,54,61)(H,55,64)(H,56,63)(H,57,66)(H,58,65)(H,67,68)(H4,46,47,50)(H4,48,49,51)/t29-,30-,31-,32-,33-,36-/m0/s1

InChIKey

ZBRXWGQCHSFAHM-MWSMAVIUSA-N

LogP

-2.818660000000017

Topological Polar Surface Area

411.0499999999999 Ų

Hydrogen Bond Donor/Acceptor

19 / 24

Complexity

1730

Synonyms & References

English

  • TYR-GLY-GLY-PHE-MET-ARG-ARG-VAL
  • ADRENORPHIN
  • Adrenorphin, Free Acid
  • H-TYR-GLY-GLY-PHE-MET-ARG-ARG-VAL-OH
  • Metorphamide (free acid)
  • Metorphamide (free acid), Adrenorphin (free acid)
  • METORPHAMIDE
  • METORPHINAMIDE
  • Metorphacid
  • L-Tyrosylglycylglycyl-L-phenylalanyl-L-methionyl-L-arginyl-L-arginyl-L-valine (ACI)
  • Adrenorphin (human), 8-L-valine- (9CI)
  • 184: PN: WO0069900 SEQID: 850 unclaimed sequence
  • 219: PN: WO0069900 SEQID: 891 unclaimed sequence
  • 247: PN: WO0069900 SEQID: 927 unclaimed sequence
  • 687: PN: US20090175821 SEQID: 850 claimed protein
  • 6: PN: WO2008011381 SEQID: 62 unclaimed sequence
  • 7: PN: WO2004073646 TABLE: 3 unclaimed sequence
  • YGGFMRRV
  • DTXSID80745609
  • 88866-92-6
  • SCHEMBL5525997
  • Adrenorphin, >=95% (HPLC)
  • (2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylsulfanylbutanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-methylbutanoic acid
  • L-Tyrosylglycylglycyl-L-phenylalanyl-L-methionyl-N~5~-(diaminomethylidene)-L-ornithyl-N~5~-(diaminomethylidene)-L-ornithyl-L-valine

MDL Number

MFCD00076434

FAQ

What regulatory guidelines apply to L-Tyrosylglycylglycyl-L-phenylalanyl-L-methionyl-N~5~-(diaminomethylidene)-L-ornithyl-N~5~-(diaminomethylidene)-L-ornithyl-L-valine (CAS: 88866-92-6)?

L-Tyrosylglycylglycyl-L-phenylalanyl-L-methionyl-N~5~-(diaminomethylidene)-L-ornithyl-N~5~-(diaminomethylidene)-L-ornithyl-L-valine (CAS: 88866-92-6) should comply with GHS classification, REACH regulations, and FDA/EPA related requirements. It is important to follow specific storage, handling, and disposal guidelines to ensure workplace safety and environmental protection.

Are there alternatives to L-Tyrosylglycylglycyl-L-phenylalanyl-L-methionyl-N~5~-(diaminomethylidene)-L-ornithyl-N~5~-(diaminomethylidene)-L-ornithyl-L-valine (CAS: 88866-92-6) in synthesis?

In synthesis, alternatives to L-Tyrosylglycylglycyl-L-phenylalanyl-L-methionyl-N~5~-(diaminomethylidene)-L-ornithyl-N~5~-(diaminomethylidene)-L-ornithyl-L-valine (CAS: 88866-92-6) include its analogs and isomers, as well as common alternative reagents such as various amino acids and peptides. These alternatives can be considered based on the specific application and desired properties.

What is the market or research trend for L-Tyrosylglycylglycyl-L-phenylalanyl-L-methionyl-N~5~-(diaminomethylidene)-L-ornithyl-N~5~-(diaminomethylidene)-L-ornithyl-L-valine (CAS: 88866-92-6)?

The market for L-Tyrosylglycylglycyl-L-phenylalanyl-L-methionyl-N~5~-(diaminomethylidene)-L-ornithyl-N~5~-(diaminomethylidene)-L-ornithyl-L-valine (CAS: 88866-92-6) is driven by its use in pharmaceuticals and research. Recent trends indicate growing interest in its application for drug discovery and development, with ongoing research exploring its potential in various biological systems and therapeutic areas.

How should waste containing L-Tyrosylglycylglycyl-L-phenylalanyl-L-methionyl-N~5~-(diaminomethylidene)-L-ornithyl-N~5~-(diaminomethylidene)-L-ornithyl-L-valine (CAS: 88866-92-6) be handled?

Waste containing L-Tyrosylglycylglycyl-L-phenylalanyl-L-methionyl-N~5~-(diaminomethylidene)-L-ornithyl-N~5~-(diaminomethylidene)-L-ornithyl-L-valine (CAS: 88866-92-6) should be collected in secure, labeled containers and disposed of through professional waste disposal services. Proper incineration or other environmentally safe methods should be employed to ensure the waste is handled in compliance with local regulations and environmental protection standards.

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