3-Bromoimidazo[1,2-A]pyridine-6-carboxylic acid

Basic Information

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CAS Number

886362-00-1

Molecular Formula

C8H5BrN2O2

Molecular Weight

241.04 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Physical State

Solid

Melting Point

305-308°

Density

1.89

Refractive Index

1.728

SMILES

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C1=CC2=NC=C(N2C=C1C(=O)O)Br

InChI

InChI=1S/C8H5BrN2O2/c9-6-3-10-7-2-1-5(8(12)13)4-11(6)7/h1-4H,(H,12,13)

InChIKey

VLYJTINXFYEGOO-UHFFFAOYSA-N

LogP

1.7949999999999997

Topological Polar Surface Area

54.599999999999994 Å²

Hydrogen Bond Donor/Acceptor

1 / 4

Complexity

224

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

3-Bromoimidazo[1,2-a]pyridine-6-carboxylic acid
3-Bromoimidazo[1,2-a]pyridine-6-carboxylic acid hydrate
Imidazo[1,2-a]pyridine-6-carboxylicacid, 3-bromo-
METHYL 3-BROMOIMIDAZO[1,2-A]PYRIDINE-6-CARBOXYLATE
3-Bromoimidazo[1,2-a]pyridine-6-carboxylic acid (ACI)
SY031597
DTXSID40585927
CS-0060680
MFCD07021511
SCHEMBL19950854
8X-0865
3-Bromoimidazo[1,2-a]pyridine-6-carboxylic acid, AldrichCPR
DB-078029
J-512101
886362-00-1
AKOS005071347
3-BROMOIMIDAZO[1,2-A]PYRIDINE-6-CARBOXYLICACID
3-bromoH-imidazo[1,2-a]pyridine-6-carboxylic acid
3-BROMOIMIDAZO[1,2-A]PYRIDINE-6-CARBOXYLIC ACID
EN300-7386123

MDL Number

MFCD07021511

Customs Code

2933990090

FAQ

What are the physical and chemical properties of 3-Bromoimidazo[1,2-A]pyridine-6-carboxylic acid (CAS: 886362-00-1)?

3-Bromoimidazo[1,2-A]pyridine-6-carboxylic acid is a crystalline solid with a molecular weight of approximately 288.03 g/mol. It has a low solubility in water but is more soluble in organic solvents like dichloromethane and acetonitrile. The compound is known for its moderate reactivity, particularly in nucleophilic substitution reactions at the bromo position. pH stability and light sensitivity are also important factors to consider.

How is 3-Bromoimidazo[1,2-A]pyridine-6-carboxylic acid (CAS: 886362-00-1) typically synthesized?

3-Bromoimidazo[1,2-A]pyridine-6-carboxylic acid can be synthesized via bromination of 6-carboxy-3-imidazo[1,2-a]pyridine using N-bromosuccinimide (NBS) in the presence of a radical initiator like AIBN. The reaction proceeds under UV light and generates a product with a high yield. This method provides a controlled and selective synthesis of the desired compound.

What industries use 3-Bromoimidazo[1,2-A]pyridine-6-carboxylic acid (CAS: 886362-00-1)?

3-Bromoimidazo[1,2-A]pyridine-6-carboxylic acid is primarily used in pharmaceutical research for the development of new drugs and in the synthesis of chemical intermediates. It also finds applications in the field of materials science, particularly in the development of sensors and semiconductors due to its unique electronic properties.

What precautions should be taken when handling 3-Bromoimidazo[1,2-A]pyridine-6-carboxylic acid (CAS: 886362-00-1)?

When handling 3-Bromoimidazo[1,2-A]pyridine-6-carboxylic acid, it is crucial to wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. The compound should be used in a well-ventilated area or a fume hood to avoid inhalation. Spills should be cleaned up carefully, and the Material Safety Data Sheet (MSDS) should be consulted for detailed spill procedures. Always follow standard laboratory safety guidelines and handle with caution to prevent potential skin contact or ingestion.