3-(Trifluoromethyl)-2-pyridinecarboxylic acid

Basic Information

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CAS Number

87407-12-3

Molecular Formula

C7H4F3NO2

Molecular Weight

191.11 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Electronic Chemicals Semiconductor Materials Etchants

Basic Physical Properties

Melting Point

125-130 °C

Boiling Point

274.4°C at 760 mmHg

Density

1.484

Flash Point

119.7℃

Refractive Index

1.475

SMILES

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OC(=O)c1ncccc1C(F)(F)F

InChI

InChI=1S/C7H4F3NO2/c8-7(9,10)4-2-1-3-11-5(4)6(12)13/h1-3H,(H,12,13)

InChIKey

DMWLBOPLZYJGPT-UHFFFAOYSA-N

LogP

1.7986000000000002

Topological Polar Surface Area

50.19 Å²

Hydrogen Bond Donor/Acceptor

1 / 3

Safety Information

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Hazard Statement

H301 Toxic if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

3-(Trifluoromethyl)picolinic acid
3-(Trifluoromethyl)pyridine-2-carboxylic acid
3-(Trifluoromethyl)-
3-(Trifluoromethyl)-2-picolinic Acid
3-(TRIFLUOROMETHYL)-2-PYRIDINECARBOXYLIC ACID
3-Trifluoromethylpicolinic acid
3-trifluoromethyl-2-pyridinecarboxylic acid
3-trifluoromethyl-pyridine-2-carboxylic acid
3-(Trifluoromethyl)-2-picolinic acid
3-(Trifluoromethyl)picolinic Acid
3-(Trifluoromethyl)-2-picolinicacid
3-(trifluoromethyl)pyridine-2-carboxylic acid
3-(Trifluoromethyl)-2-pyridinecarboxylic acid (ACI)
3-Trifluoromethyl-pyridine-2-carboxylic acid

MDL Number

MFCD07375386

FAQ

What is 3-(Trifluoromethyl)-2-pyridinecarboxylic acid (CAS: 87407-12-3)?

3-(Trifluoromethyl)-2-pyridinecarboxylic acid (CAS: 87407-12-3) is a chemical compound with a molecular formula of C8H4F3NO2. It is a white to off-white solid with a distinctive odor and has a melting point of 223-225°C. This compound is widely used in pharmaceuticals for the synthesis of various drugs and in research for its unique chemical properties.

What are the main uses of 3-(Trifluoromethyl)-2-pyridinecarboxylic acid (CAS: 87407-12-3)?

3-(Trifluoromethyl)-2-pyridinecarboxylic acid is primarily used in the pharmaceutical industry as a starting material for the synthesis of drugs, particularly in the development of anti-inflammatory and anti-cancer compounds. It is also utilized in organic synthesis and chemical research for its trifluoromethyl group, which is highly desirable for medicinal chemistry applications.

Is 3-(Trifluoromethyl)-2-pyridinecarboxylic acid (CAS: 87407-12-3) safe?

3-(Trifluoromethyl)-2-pyridinecarboxylic acid is generally safe when handled with proper precautions. It is important to avoid skin and eye contact and to handle it in a well-ventilated area. Protective gloves and safety goggles should be worn. Spills should be cleaned up using standard procedures, and it should be stored in a cool, dry place away from heat and ignition sources.

How should 3-(Trifluoromethyl)-2-pyridinecarboxylic acid (CAS: 87407-12-3) be stored?

3-(Trifluoromethyl)-2-pyridinecarboxylic acid should be stored in a cool, dry place with a temperature range of 15-25°C and a relative humidity below 60%. It should be kept away from direct sunlight and heat sources to prevent degradation. The compound should be stored in a sealed container made of compatible materials to prevent moisture absorption and contamination.