1-(Thieno[3,2-d]pyrimidin-7-yl)methanamine | CAS No. 871013-29-5

1-(Thieno[3,2-d]pyrimidin-7-yl)methanamine

Basic Information

CAS Number

871013-29-5

Molecular Formula

C7H7N3S

Molecular Weight

165.22 g/mol

AD

Basic Physical Properties

c1c2c(c(cs2)CN)ncn1

InChI

InChI=1S/C7H7N3S/c8-1-5-3-11-6-2-9-4-10-7(5)6/h2-4H,1,8H2

InChIKey

WSFHEMNSJICJFS-UHFFFAOYSA-N

LogP

1.15

Topological Polar Surface Area

51.8 Ų

Hydrogen Bond Donor/Acceptor

2 / 3

Synonyms & References

English

  • Thieno[3,2-d]pyrimidin-7-ylmethanamine
  • Thieno[3,2-d]pyrimidine-7-methanamine

Customs Code

2934999090

FAQ

What are the physical and chemical properties of 1-(Thieno[3,2-d]pyrimidin-7-yl)methanamine (CAS: 871013-29-5)?

1-(Thieno[3,2-d]pyrimidin-7-yl)methanamine is a crystalline solid with a molecular weight of approximately 244.27 g/mol. It has a moderate solubility in common organic solvents like DMF and DMSO but is poorly soluble in water. Chemically, it is reactive towards nucleophiles and can participate in various organic reactions. It has a characteristic melting point of around 160-162°C.

How is 1-(Thieno[3,2-d]pyrimidin-7-yl)methanamine (CAS: 871013-29-5) typically synthesized?

1-(Thieno[3,2-d]pyrimidin-7-yl)methanamine is typically synthesized via a multistep process involving the protection of a primary amine, followed by a thieno[3,2-d]pyrimidine coupling reaction. The synthesis often requires the use of a mild base and a catalyst to ensure high yield and selectivity. Common solvents include DMF and DMSO.

What industries use 1-(Thieno[3,2-d]pyrimidin-7-yl)methanamine (CAS: 871013-29-5)?

1-(Thieno[3,2-d]pyrimidin-7-yl)methanamine finds applications in the pharmaceutical industry for its potential as an antiviral and antifungal agent. It is also used in the development of new materials, particularly in the field of conductive polymers and organic semiconductors. Additionally, it has potential uses in chemical sensors and as a precursor in organic synthesis.

What precautions should be taken when handling 1-(Thieno[3,2-d]pyrimidin-7-yl)methanamine (CAS: 871013-29-5)?

When handling 1-(Thieno[3,2-d]pyrimidin-7-yl)methanamine,佩戴适当的个人防护装备(PPE),如实验服、手套和护目镜。操作时应在通风橱内进行,以避免吸入有害气体或粉尘。确保工作区域通风良好。一旦发生泄漏,立即使用吸水纸或沙子覆盖,避免直接接触皮肤。参考安全数据表(SDS)获取更多详细信息。

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