1,3-Dioxan-5-ol

Basic Information

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CAS Number

86687-05-0

Molecular Formula

C4H8O3

Molecular Weight

104.11 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Boiling Point

192-193 °C

Density

1.203 g/mL at 25 °C

Flash Point

170 °F

Refractive Index

n20/D 1.451(lit.)

SMILES

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OC1COCOC1

InChI

InChI=1S/C4H8O3/c5-4-1-6-3-7-2-4/h4-5H,1-3H2

InChIKey

VCKSNYNNVSOWEE-UHFFFAOYSA-N

LogP

-0.6484000000000001

Topological Polar Surface Area

38.69 Å²

Hydrogen Bond Donor/Acceptor

1 / 3

Synonyms & References

English

1,3-Dioxan-5-ol
Glycerol formal
1,3-Dioxolane-4-methanol
Glycerol ForMal (Mixture of 1,3-Dioxan-5-ol and 4-HydroxyMethyldioxolane)
甘油缩甲醛

MDL Number

MFCD00014645

FAQ

What are the physical and chemical properties of 1,3-Dioxan-5-ol (CAS: 86687-05-0)?

1,3-Dioxan-5-ol (CAS: 86687-05-0) is a colorless, viscous liquid at room temperature with a low melting point and high boiling point. Its molecular weight is approximately 108.11 g/mol. It is slightly soluble in water but miscible with most organic solvents. Chemically, it is less reactive compared to other alcohols, with limited reactivity towards common functional group transformations.

How is 1,3-Dioxan-5-ol (CAS: 86687-05-0) typically synthesized?

1,3-Dioxan-5-ol can be synthesized through the reduction of 1,3-dioxane using sodium borohydride or lithium aluminum hydride as the reducing agent. The synthesis typically involves selective reduction of the 1,3-dioxane ring to form the alcohol, with high yield and good selectivity.

What industries use 1,3-Dioxan-5-ol (CAS: 86687-05-0)?

1,3-Dioxan-5-ol (CAS: 86687-05-0) is primarily used in the pharmaceutical industry for the synthesis of various organic compounds. It is also utilized in polymer science for the preparation of certain polymers, and in the chemical sensing sector for the development of gas sensors. Additionally, it has applications in the semiconductor industry as a cleaning solvent.

What precautions should be taken when handling 1,3-Dioxan-5-ol (CAS: 86687-05-0)?

When handling 1,3-Dioxan-5-ol (CAS: 86687-05-0), appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat should be worn. Ensure work is conducted in a well-ventilated area or a fume hood to minimize inhalation risks. Spills should be handled carefully using appropriate absorbent materials, and the material safety data sheet (MSDS) should be consulted for specific spill clean-up procedures.