(6alpha,11beta)-21-Acetoxy-11-hydroxy-6-methyl-3,20-dioxopregna-1,4-dien-17-yl propionate | CAS No. 86401-95-8

(6alpha,11beta)-21-Acetoxy-11-hydroxy-6-methyl-3,20-dioxopregna-1,4-dien-17-yl propionate

Basic Information

CAS Number

86401-95-8

Molecular Formula

C27H36O7

Molecular Weight

472.58 g/mol

AD

Basic Physical Properties

Boiling Point

595.8°C at 760 mmHg

CCC(=O)O[C@@]1(CC[C@H]2[C@@H]3C[C@H](C)C4=CC(=O)C=C[C@]4(C)[C@H]3[C@@H](O)C[C@@]21C)C(=O)COC(=O)C

InChI

InChI=1S/C27H36O7/c1-6-23(32)34-27(22(31)14-33-16(3)28)10-8-19-18-11-15(2)20-12-17(29)7-9-25(20,4)24(18)21(30)13-26(19,27)5/h7,9,12,15,18-19,21,24,30H,6,8,10-11,13-14H2,1-5H3/t15-,18-,19-,21-,24+,25-,26-,27-/m0/s1

InChIKey

DALKLAYLIPSCQL-YPYQNWSCSA-N

LogP

3.335300000000002

Topological Polar Surface Area

106.97000000000003 Ų

Hydrogen Bond Donor/Acceptor

1 / 7

Complexity

980

Safety Information

View Safety Information

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation
H319 Causes serious eye irritation
Serious eye damage/eye irritation
H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

  • Methylprednisolone aceponate
  • [(6S,8R,9R,10S,11S,13S,14S,17R)-17-(2-Acetyloxyacetyl)-11-hydroxy-6,10,13-trimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl] propanoate
  • 6α-Methyl Prednisolone Aceponate
  • 6α-Methyl Prednisolo
  • Advantan
  • Methylprednisolone aceponate [INN]
  • Methylprednisoloni aceponas [Latin]
  • C27H36O7
  • ZK91588
  • Aceponato de metilprednisolona [Spanish]
  • Aceponate de methylprednisolone [French]
  • ET54W9J4U2
  • Methylprednisolone aceponate (INN)
  • (6S,8S
  • (6S,8S,9S,10R,11S,13S,14S,17R)-17-(2-acetoxyacetyl)-11-hydroxy-6,10,13-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl propionate

MDL Number

MFCD00866150

FAQ

What is (6alpha,11beta)-21-Acetoxy-11-hydroxy-6-methyl-3,20-dioxopregna-1,4-dien-17-yl propionate (CAS: 86401-95-8)?

(6alpha,11beta)-21-Acetoxy-11-hydroxy-6-methyl-3,20-dioxopregna-1,4-dien-17-yl propionate (CAS: 86401-95-8) is a semi-synthetic progestin derivative with potential hormonal properties. It is a white or almost white solid with a molecular weight of approximately 561.6 g/mol. This compound is used in research and pharmaceutical applications for its hormonal activity.

What are the main uses of (6alpha,11beta)-21-Acetoxy-11-hydroxy-6-methyl-3,20-dioxopregna-1,4-dien-17-yl propionate (CAS: 86401-95-8)?

(6alpha,11beta)-21-Acetoxy-11-hydroxy-6-methyl-3,20-dioxopregna-1,4-dien-17-yl propionate (CAS: 86401-95-8) is primarily used in the development of hormonal therapies, particularly in the treatment of reproductive disorders and certain gynecological conditions. It is also used in research for its hormonal properties.

Is (6alpha,11beta)-21-Acetoxy-11-hydroxy-6-methyl-3,20-dioxopregna-1,4-dien-17-yl propionate (CAS: 86401-95-8) safe?

(6alpha,11beta)-21-Acetoxy-11-hydroxy-6-methyl-3,20-dioxopregna-1,4-dien-17-yl propionate (CAS: 86401-95-8) is generally safe when used under the guidance of a healthcare professional. However, it should be handled with caution due to its hormonal properties. Protective measures include avoiding contact with skin and eyes, and storing it in a cool, dry place away from direct sunlight.

How should (6alpha,11beta)-21-Acetoxy-11-hydroxy-6-methyl-3,20-dioxopregna-1,4-dien-17-yl propionate (CAS: 86401-95-8) be stored?

(6alpha,11beta)-21-Acetoxy-11-hydroxy-6-methyl-3,20-dioxopregna-1,4-dien-17-yl propionate (CAS: 86401-95-8) should be stored in a tightly closed container at room temperature, away from direct sunlight and moisture. Maintain a cool, dry environment to preserve its chemical integrity and stability.

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