7-Methoxy-1,2,3,4-tetrahydro-1-naphthalenecarboxylic acid | CAS No. 85858-95-3

7-Methoxy-1,2,3,4-tetrahydro-1-naphthalenecarboxylic acid

Basic Information

CAS Number

85858-95-3

Molecular Formula

C12H14O3

Molecular Weight

206.24 g/mol

AD

Basic Physical Properties

Boiling Point

374.977 ℃ at 760 mmHg

COC1=CC2=C(CCCC2C(=O)O)C=C1

InChI

InChI=1S/C12H14O3/c1-15-9-6-5-8-3-2-4-10(12(13)14)11(8)7-9/h5-7,10H,2-4H2,1H3,(H,13,14)

InChIKey

WJNRAOKRAWFGFS-UHFFFAOYSA-N

LogP

2.1997

Topological Polar Surface Area

46.53 Ų

Hydrogen Bond Donor/Acceptor

1 / 3

Complexity

239

Synonyms & References

English

  • 1,2,3,4-TETRAHYDRO-7-METHOXY-1-NAPHTHALENECARBOXYLIC ACID
  • 7-methoxy-1,2,3,4-tetrahydronaphthalene-1-carboxylicacid
  • SCHEMBL1844488
  • 1-Naphthalenecarboxylicacid,1,2,3,4-tetrahydro-7-methoxy-
  • FT-0740922
  • WJNRAOKRAWFGFS-UHFFFAOYSA-N
  • EN300-270113
  • Z1317635417
  • 7-methoxy-1,2,3,4-tetrahydronaphthalene-1-carboxylic acid
  • DTXSID60534114
  • 85858-95-3
  • CS-0243956
  • AKOS016005566
  • 1,2,3,4-Tetrahydro-7-methoxy-1-naphthalenecarboxylicacid
  • 7-Methoxy-1,2,3,4-tetrahydronaphthalene-1-carboxylic acid
  • 1,2,3,4-tetrahydro-7-methoxy-1-Naphthalenecarboxylic acid
  • (R,S)-7-methoxy-1,2,3,4-tetrahydro-naphthalene-1-carboxylic acid
  • 7-Methoxy-1,2,3,4-tetrahydro-[1]naphthoesaeure
  • 7-methoxy-1,2,3,4-tetrahydro-[1]naphthoic acid
  • 7-methoxy-1,2,3,4-tetrahydro-1-naphthylcarboxylic acid
  • 7-Methoxy-1,2,3,4-tetrahydro-naphthalene-1-carboxylic acid
  • 7-methoxy-3,4-dihydronaphthalen-1-yl-carboxylic acid
  • 1-Naphthoicacid, 1,2,3,4-tetrahydro-7-methoxy- (6CI)

MDL Number

MFCD06659045

Customs Code

2918990090

FAQ

What are the physical and chemical properties of 7-Methoxy-1,2,3,4-tetrahydro-1-naphthalenecarboxylic acid (CAS: 85858-95-3)?

7-Methoxy-1,2,3,4-tetrahydro-1-naphthalenecarboxylic acid is a white crystalline solid with a molecular weight of approximately 226.22 g/mol. It has a melting point of 120-122°C and is slightly soluble in water. Chemically, it is reactive towards bases and can form salts. The compound is stable under normal conditions but can react with strong acids and bases.

How is 7-Methoxy-1,2,3,4-tetrahydro-1-naphthalenecarboxylic acid (CAS: 85858-95-3) typically synthesized?

7-Methoxy-1,2,3,4-tetrahydro-1-naphthalenecarboxylic acid is commonly synthesized by the methylation of 1-naphthalenecarboxylic acid followed by reduction to form the tetrahydro derivative. This reaction typically involves the use of methanol and a strong acid catalyst. The yield is usually around 80-85%, and the product can be isolated by recrystallization from water.

What industries use 7-Methoxy-1,2,3,4-tetrahydro-1-naphthalenecarboxylic acid (CAS: 85858-95-3)?

7-Methoxy-1,2,3,4-tetrahydro-1-naphthalenecarboxylic acid is used in the pharmaceutical industry for the synthesis of certain drugs. It is also utilized in the production of polymers and as a precursor in the development of sensors and semiconductors due to its chemical reactivity and stability.

What precautions should be taken when handling 7-Methoxy-1,2,3,4-tetrahydro-1-naphthalenecarboxylic acid (CAS: 85858-95-3)?

When handling 7-Methoxy-1,2,3,4-tetrahydro-1-naphthalenecarboxylic acid, it is important to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. The compound should be stored in a cool, dry place, away from strong acids and bases. In case of a spill, it should be cleaned up immediately, and appropriate handling procedures should be followed as outlined in the safety data sheet (SDS).

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