[2-Chloro-6-(trifluoromethyl)phenyl]boronic acid

Basic Information

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CAS Number

851756-52-0

Molecular Formula

C7H5BClF3O2

Molecular Weight

224.37 g/mol

Chemical Classification

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

116-120°C

SMILES

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OB(c1c(Cl)cccc1C(F)(F)F)O

InChI

InChI=1S/C7H5BClF3O2/c9-5-3-1-2-4(7(10,11)12)6(5)8(13)14/h1-3,13-14H

InChIKey

ARGDVPMTQZNUBG-UHFFFAOYSA-N

LogP

1.0386

Topological Polar Surface Area

40.46 Å²

Hydrogen Bond Donor/Acceptor

2 / 2

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

2-Chloro-6-(trifluoromethyl)phenylboronic acid
[2-chloro-6-(trifluoromethyl)phenyl]boronic acid
2-CHLORO-6-(TRIFLUOROMETHYL)BENZENEBORONIC ACID
Boronic acid,B-[2-chloro-6-(trifluoromethyl)phenyl]-

MDL Number

MFCD09037968

Customs Code

2931900090

FAQ

What regulatory guidelines apply to [2-Chloro-6-(trifluoromethyl)phenyl]boronic acid (CAS: 851756-52-0)?

The regulatory guidelines for [2-Chloro-6-(trifluoromethyl)phenyl]boronic acid (CAS: 851756-52-0) include the Globally Harmonized System of Classification and Labeling of Chemicals (GHS), REACH regulations in the European Union, and FDA guidelines in the United States. Specific handling and disposal procedures must comply with local and national regulations. Additionally, EPA requirements may apply for waste management and environmental protection.

Are there alternatives to [2-Chloro-6-(trifluoromethyl)phenyl]boronic acid (CAS: 851756-52-0) in synthesis?

There are alternative boronic acids that can be used in synthesis, such as 2-Bromo-6-(trifluoromethyl)phenylboronic acid or 2-Iodo-6-(trifluoromethyl)phenylboronic acid. These alternatives offer similar functionalities but may have different reactivity and synthetic applications. The choice of alternative depends on the specific reaction conditions and desired product.

What is the market or research trend for [2-Chloro-6-(trifluoromethyl)phenyl]boronic acid (CAS: 851756-52-0)?

The market for [2-Chloro-6-(trifluoromethyl)phenyl]boronic acid (CAS: 851756-52-0) is growing due to its use in organic synthesis, particularly in Suzuki couplings and other cross-coupling reactions. Research trends focus on developing more efficient synthetic methods and exploring its applications in drug discovery and materials science.

How should waste containing [2-Chloro-6-(trifluoromethyl)phenyl]boronic acid (CAS: 851756-52-0) be handled?

Waste containing [2-Chloro-6-(trifluoromethyl)phenyl]boronic acid (CAS: 851756-52-0) should be collected in appropriate containers and stored in a well-ventilated area away from ignition sources. Incineration or professional waste disposal services should be used for disposal. Environmental protection precautions include minimizing exposure and following local and national regulations for hazardous waste management.