3-Bromo-7-chloroquinoline

Basic Information

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CAS Number

84973-05-7

Molecular Formula

C9H5BrClN

Molecular Weight

242.5 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Density

1.673±0.06 g/cm3 (20 ºC 760 Torr),

SMILES

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Clc1ccc2c(c1)ncc(c2)Br

InChI

InChI=1S/C9H5BrClN/c10-7-3-6-1-2-8(11)4-9(6)12-5-7/h1-5H

InChIKey

AULIHGFJRSSSKE-UHFFFAOYSA-N

LogP

3.6507000000000005

Topological Polar Surface Area

12.89 Å²

Hydrogen Bond Donor/Acceptor

0 / 1

Synonyms & References

English

3-Bromo-7-chloroquinoline
Quinoline,3-bromo-7-chloro-
3-bromo-7-chloroquinoline

MDL Number

MFCD04973785

FAQ

What are the physical and chemical properties of 3-Bromo-7-chloroquinoline (CAS: 84973-05-7)?

3-Bromo-7-chloroquinoline (CAS: 84973-05-7) is a crystalline solid with a molecular weight of approximately 244.01 g/mol. It has a high melting point around 240-242°C. The compound is poorly soluble in water but soluble in common organic solvents like ethanol and acetone. It is moderately reactive with bases and reducing agents but stable under normal conditions. Its physical and chemical properties make it useful in various synthetic reactions.

How is 3-Bromo-7-chloroquinoline (CAS: 84973-05-7) typically synthesized?

3-Bromo-7-chloroquinoline (CAS: 84973-05-7) is commonly synthesized via the bromination of 7-chloroquinoline followed by quenching with a base. This process requires the use of bromine and a suitable base like sodium hydroxide. The reaction typically has a good yield and high selectivity, making it a reliable method for producing this compound.

What industries use 3-Bromo-7-chloroquinoline (CAS: 84973-05-7)?

3-Bromo-7-chloroquinoline (CAS: 84973-05-7) is used in the pharmaceutical industry for the synthesis of certain drugs, and in the electronics industry for the production of semiconductors. It also has applications in the polymer industry, where it can be used as a precursor for the synthesis of functional polymers. Additionally, it is employed in sensor technology for its unique electronic properties.

What precautions should be taken when handling 3-Bromo-7-chloroquinoline (CAS: 84973-05-7)?

When handling 3-Bromo-7-chloroquinoline (CAS: 84973-05-7), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. This compound should be stored in a cool, dry place, away from direct sunlight and flammable materials. In case of a spill, it should be handled in a fume hood, and appropriate safety data sheets (SDS) should be consulted for detailed emergency procedures.