2-Chloro-1-(4-fluorobenzyl)-1H-benzimidazole

Basic Information

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CAS Number

84946-20-3

Molecular Formula

C14H10ClFN2

Molecular Weight

260.7 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Physical State

Powder

Melting Point

82.0 to 86.0 deg-C

Boiling Point

432.3℃ at 760 mmHg

SMILES

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FC1=CC=C(C=C1)CN2C(Cl)=NC3=CC=CC=C23

InChI

InChI=1S/C14H10ClFN2/c15-14-17-12-3-1-2-4-13(12)18(14)9-10-5-7-11(16)8-6-10/h1-8H,9H2

InChIKey

PGXALMVNIRPELS-UHFFFAOYSA-N

LogP

3.8771000000000013

Topological Polar Surface Area

17.82 Å²

Hydrogen Bond Donor/Acceptor

0 / 2

Complexity

281

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

2-Chloro-1-(4-fluorobenzyl)-1H-benzo[d]imidazole
N-METHYL-N-(-CHLOROETHYL) ANILINE
3-(4'-FLUOROBENZY)-2-CHLOROBENZIMIDAZOLE
1-(4'-FLUOROBENZYL)-2-CHLOROBENZIMIDAZOLE
1-(4-FLUOROBENZYL)-2-CHLORO-BENZIMIDAZOLE
1-(4-FLUOROPHENYLMETHYL)-2-CHLOROBENZIMIDAZOLE
2-CHLORO-1-(4-FLUOROBENZYL)-1H-BENZIMIDAZOLE
2-Chloro-1-[(4-fluorophenyl)methyl]-1H-benzimidazole
2-Chloro-1-(4-fluorobenzyl)benzimidazole
3-(4-Fluorobenzyl)-2-Chlorobenzimidazole
1-(4-fluorobenzyl)-2-chloro-1H-benzo[d]imidazole
1-(4-FLUOROBENZYL)-2-CHLOROBENZIMIDAZOLE
2-chloro-1-[(4-fluorophenyl)methyl]benzimidazole
: 1-(4-Fluorobenzyl)-2-chlorobenzimidazole
2-Chloro-1-(4-fluoro-benzyl)-1H-benzoimidazole
572KOO4QPT
1H-Benzimidazole, 2-chloro-1-[(4-fluorophenyl)methyl]-
2-Chloro-1-((4-fluoropheny

MDL Number

MFCD00008090

Customs Code

2933990090

FAQ

What is 2-Chloro-1-(4-fluorobenzyl)-1H-benzimidazole (CAS: 84946-20-3)?

2-Chloro-1-(4-fluorobenzyl)-1H-benzimidazole (CAS: 84946-20-3) is a synthetic organic compound with the chemical formula C14H10ClF3N2. It belongs to the benzimidazole class, characterized by a five-membered heterocyclic ring with two nitrogen atoms. The compound features chloro and fluorobenzyl substituents, contributing to its reactivity and potential applications in pharmaceuticals. It is typically a solid at room temperature and exhibits moderate solubility in organic solvents.

What are the main uses of 2-Chloro-1-(4-fluorobenzyl)-1H-benzimidazole (CAS: 84946-20-3)?

2-Chloro-1-(4-fluorobenzyl)-1H-benzimidazole (CAS: 84946-20-3) is primarily used as a pharmaceutical intermediate in the synthesis of drugs targeting neurological disorders. Its unique structure also finds applications in agrochemicals and materials science due to its functional groups. The compound is valued for its ability to modulate biological activity, making it relevant in research and development of therapeutic agents.

Is 2-Chloro-1-(4-fluorobenzyl)-1H-benzimidazole (CAS: 84946-20-3) safe?

The safety of 2-Chloro-1-(4-fluorobenzyl)-1H-benzimidazole (CAS: 84946-20-3) depends on exposure conditions. It is classified as a potential irritant and should be handled with appropriate safety measures, such as gloves and ventilation. While specific toxicity data is limited, adherence to standard chemical safety protocols is recommended. Always consult safety data sheets (SDS) for detailed information on handling and disposal.

How should 2-Chloro-1-(4-fluorobenzyl)-1H-benzimidazole (CAS: 84946-20-3) be stored?

2-Chloro-1-(4-fluorobenzyl)-1H-benzimidazole (CAS: 84946-20-3) should be stored in a sealed, cool (below 25°C), and dry environment, away from light. It is best kept in airtight containers to prevent moisture absorption and maintain stability. Avoid exposure to heat or incompatible substances to ensure long-term preservation and safety.