4-[(3-Chloro-4-fluorophenyl)amino]-6-[3-(4-morpholinyl)propoxy]-7-quinazolinol

Basic Information

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CAS Number

847949-49-9

Molecular Formula

C21H22ClFN4O3

Molecular Weight

432.88 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Melting Point

117-120?C

Boiling Point

606.4°C at 760 mmHg

Density

1.386

Flash Point

320.5°C

Refractive Index

1.65

SMILES

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c1cc(c(cc1Nc2c3cc(c(cc3ncn2)O)OCCCN4CCOCC4)Cl)F

InChI

InChI=1S/C21H22ClFN4O3/c22-16-10-14(2-3-17(16)23)26-21-15-11-20(19(28)12-18(15)24-13-25-21)30-7-1-4-27-5-8-29-9-6-27/h2-3,10-13,28H,1,4-9H2,(H,24,25,26)

InChIKey

IFMMYZUUCFPEHR-UHFFFAOYSA-N

LogP

3.9726000000000035

Topological Polar Surface Area

79.74000000000001 Å²

Hydrogen Bond Donor/Acceptor

2 / 7

Synonyms & References

English

7-Quinazolinol,4-[(3-chloro-4-fluorophenyl)amino]-6-[3-(4-morpholinyl)propoxy]-
O-Desmethyl Gefitinib
4-(3-chloro-4-fluoroanilino)-6-(3-morpholin-4-ylpropoxy)-1H-quinazolin-7-one
4-[(3-chloro-4-fluorophenyl)amino]-6-[3-(4-morpholinyl)propoxy]-7-Quinazolinol
4-(3'-chloro-4'-fluoroanilino)-7-hydroxy-6-(3-morpholinopropoxy)quinazoline
7-Quinazolinol,4-[(3-chloro-4-fluorophenyl)amino]-6-[3-(4-morpholinyl)propoxy]
O-Demethyl-Gefitinib
4-((3-chloro-4-fluorophenyl)amino)-6-(3-morpholinopropoxy)quinazolin-7-ol

MDL Number

MFCD09952182

Customs Code

2934999090

FAQ

What is 4-[(3-Chloro-4-fluorophenyl)amino]-6-[3-(4-morpholinyl)propoxy]-7-quinazolinol (CAS: 847949-49-9)?

4-[(3-Chloro-4-fluorophenyl)amino]-6-[3-(4-morpholinyl)propoxy]-7-quinazolinol is a complex organic compound with the CAS number 847949-49-9. It is characterized by its quinazolinone backbone with a side chain featuring a 3-(4-morpholinyl)propoxy group and a chloro-fluoro-phenyl amino substituent.

What are the main uses of 4-[(3-Chloro-4-fluorophenyl)amino]-6-[3-(4-morpholinyl)propoxy]-7-quinazolinol (CAS: 847949-49-9)?

4-[(3-Chloro-4-fluorophenyl)amino]-6-[3-(4-morpholinyl)propoxy]-7-quinazolinol is primarily used in pharmaceutical applications, particularly in the development of antiviral and antiproliferative agents. It has potential applications in research and drug discovery.

Is 4-[(3-Chloro-4-fluorophenyl)amino]-6-[3-(4-morpholinyl)propoxy]-7-quinazolinol (CAS: 847949-49-9) safe?

4-[(3-Chloro-4-fluorophenyl)amino]-6-[3-(4-morpholinyl)propoxy]-7-quinazolinol is generally considered safe when handled with appropriate precautions. However, it is important to follow safety guidelines, including the use of personal protective equipment and proper ventilation. Ensure that the compound is stored and used in a manner that prevents inhalation or ingestion.

How should 4-[(3-Chloro-4-fluorophenyl)amino]-6-[3-(4-morpholinyl)propoxy]-7-quinazolinol (CAS: 847949-49-9) be stored?

4-[(3-Chloro-4-fluorophenyl)amino]-6-[3-(4-morpholinyl)propoxy]-7-quinazolinol should be stored in a cool, dry place away from direct sunlight and heat sources. It should be kept in a tightly sealed container to prevent degradation. The storage temperature should not exceed 25°C, and the relative humidity should be below 50%. Proper labeling and documentation are also necessary for safe storage and handling.