3'-Azido-2',3'-dideoxycytidine | CAS No. 84472-89-9

3'-Azido-2',3'-dideoxycytidine

Basic Information

CAS Number

84472-89-9

Molecular Formula

C9H12N6O3

Molecular Weight

252.23 g/mol

AD

Basic Physical Properties

C1C(C(OC1N2C=CC(=NC2=O)N)CO)N=[N+]=[N-]

InChI

InChI=1S/C9H12N6O3/c10-7-1-2-15(9(17)12-7)8-3-5(13-14-11)6(4-16)18-8/h1-2,5-6,8,16H,3-4H2,(H2,10,12,17)/t5-,6+,8+/m0/s1

InChIKey

YIEFKLOVIROQIL-SHYZEUOFSA-N

LogP

0.12656

Complexity

455

Synonyms & References

English

  • 4-amino-1-[(2R,4S,5S)-4-azido-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydropyrimidin-2-one
  • Cytidine,3'-azido-2',3'-dideoxy-
  • 4-amino-1-[(2R,4S,5S)-4-azido-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidin-2-one
  • 3'-Azido-2',3'-dideoxycytidine
  • YIEFKLOVIROQIL-SHYZEUOFSA-N
  • BS-42381
  • CHEMBL1791029
  • 2',3'-Dideoxy-3'-azidocytidine
  • NSC382318
  • 3'-Azido-2'-deoxy-D-cytidine
  • 3'-N3-ddC
  • CS-91
  • 1-((2R,4S,5S)-4-azido-5-(hydroxymethyl)tetrahydrofuran-2-yl)-4-imino-3,4-dihydropyrimidin-2(1H)-one
  • 4-amino-1-[(2R,4S,5S)-4-azido-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
  • 84472-89-9
  • AzddCyd
  • DTXSID10233443
  • MFCD00880598
  • NSC 382318
  • SCHEMBL15643018
  • 3'-Azido-ddC
  • Cytidine, 3'-azido-2',3'-dideoxy-
  • Cytidine,3'-azido-2',3'-dideoxy
  • CS 91

MDL Number

MFCD00880598

FAQ

What regulatory guidelines apply to 3'-Azido-2',3'-dideoxycytidine (CAS: 84472-89-9)?

3'-Azido-2',3'-dideoxycytidine (CAS: 84472-89-9) falls under the regulatory framework of the Globally Harmonized System of Classification and Labelling of Chemicals (GHS) for hazardous chemicals. It is also classified under REACH regulations in the European Union, which require detailed safety data sheets (SDS) for handling and disposal. In the United States, the Environmental Protection Agency (EPA) and the Food and Drug Administration (FDA) may impose additional requirements related to research and manufacturing processes.

Are there alternatives to 3'-Azido-2',3'-dideoxycytidine (CAS: 84472-89-9) in synthesis?

There are several alternatives to 3'-Azido-2',3'-dideoxycytidine (CAS: 84472-89-9) in synthesis, such as other azido-containing nucleosides like 3'-Azido-2',3'-dideoxyinosine and 3'-Azido-2',3'-dideoxythymidine. Common alternative reagents include nucleoside triphosphates and their analogs, which can serve as precursors in the synthesis of nucleoside derivatives.

What is the market or research trend for 3'-Azido-2',3'-dideoxycytidine (CAS: 84472-89-9)?

The market and research trends for 3'-Azido-2',3'-dideoxycytidine (CAS: 84472-89-9) are closely linked to its applications in antiretroviral therapy and HIV research. Recent studies are focusing on its potential as a component in novel antiretroviral drugs and as a tool for gene editing and gene therapy. Market trends indicate increasing demand for this compound due to advancements in AIDS treatment and gene modification technologies.

How should waste containing 3'-Azido-2',3'-dideoxycytidine (CAS: 84472-89-9) be handled?

Waste containing 3'-Azido-2',3'-dideoxycytidine (CAS: 84472-89-9) should be managed according to local and international hazardous waste regulations. Proper disposal methods include collection in dedicated containers, followed by incineration or professional waste disposal by certified companies. Environmental protection precautions include minimizing spills and ensuring all waste is neutralized before disposal to prevent contamination of the environment and public health.

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