6,8-Difluoro-3,4-dihydro-2(1H)-naphthalenone

Basic Information

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CAS Number

843644-23-5

Molecular Formula

C10H8F2O

Molecular Weight

182.17 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ketones

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Electronic Chemicals Semiconductor Materials Etchants

Basic Physical Properties

Melting Point

96-98°C

Boiling Point

260.6°C at 760 mmHg

Density

1.29

Flash Point

99.4°C

Refractive Index

1.523

SMILES

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c1c(cc(c2c1CCC(=O)C2)F)F

InChI

InChI=1S/C10H8F2O/c11-7-3-6-1-2-8(13)5-9(6)10(12)4-7/h3-4H,1-2,5H2

InChIKey

JDIYLARKCSUHBH-UHFFFAOYSA-N

LogP

2.0226

Topological Polar Surface Area

17.07 Å²

Hydrogen Bond Donor/Acceptor

0 / 1

Complexity

217

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

6,8-Difluoro-2-tetralone
6,8-Difluoro-3,4-dihydro-2(1H)-naphthalenone
6,8-difluoro-3,4-dihydro-1H-naphthalen-2-one
6,8-Difluoro-3,4-Dihydronaphthalen-2(1H)-One
6,8-difluoro-1,2,3,4-tetrahydronaphthalen-2-one
2(1H)-Naphthalenone, 6,8-difluoro-3,4-dihydro-
AMOT0847
JDIYLARKCSUHBH-UHFFFAOYSA-N
BCP10185
SB17761
CM14107
Z1865
ST24045000
644D235
6,8-difluoro-3,4-dihydronaphthalen-2(1 H)-one
2(1H)

MDL Number

MFCD05663016

FAQ

What are the physical and chemical properties of 6,8-Difluoro-3,4-dihydro-2(1H)-naphthalenone (CAS: 843644-23-5)?

6,8-Difluoro-3,4-dihydro-2(1H)-naphthalenone (CAS: 843644-23-5) is a white crystalline solid with a molecular weight of approximately 198.07 g/mol. It is slightly soluble in water but soluble in organic solvents such as methanol and dichloromethane. This compound is relatively stable under normal conditions but can react with strong bases and reducing agents. It has a melting point of around 70-72°C.

How is 6,8-Difluoro-3,4-dihydro-2(1H)-naphthalenone (CAS: 843644-23-5) typically synthesized?

6,8-Difluoro-3,4-dihydro-2(1H)-naphthalenone (CAS: 843644-23-5) is typically synthesized via fluoroamination of 3,4-dihydro-2(1H)-naphthalenone, using a fluoroamine derivative and a suitable catalyst. The reaction generally yields high selectivity and good to excellent yields under mild conditions. Detailed procedures can be found in various organic synthesis literature.

What industries use 6,8-Difluoro-3,4-dihydro-2(1H)-naphthalenone (CAS: 843644-23-5)?

6,8-Difluoro-3,4-dihydro-2(1H)-naphthalenone (CAS: 843644-23-5) is primarily used in the pharmaceutical industry for the synthesis of drug intermediates. It is also explored in the polymer industry for the development of advanced materials and in the sensor industry for its chemical sensing capabilities. Additionally, it has potential applications in the semiconductor industry for specific chemical treatments.

What precautions should be taken when handling 6,8-Difluoro-3,4-dihydro-2(1H)-naphthalenone (CAS: 843644-23-5)?

When handling 6,8-Difluoro-3,4-dihydro-2(1H)-naphthalenone (CAS: 843644-23-5), it is essential to work in a well-ventilated area or a fume hood. Proper personal protective equipment (PPE) should be worn, including gloves, safety glasses, and a laboratory coat. Spills should be handled carefully and cleaned up using appropriate absorbents. Always consult the Safety Data Sheet (SDS) for detailed safety information and emergency procedures.