6-Fluoro-3-(4-piperidinyl)-1,2-benzoxazole

Basic Information

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CAS Number

84163-77-9

Molecular Formula

C12H13FN2O

Molecular Weight

220.25 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Physical State

White to Yellow Solid

Melting Point

59-64 °C

Boiling Point

359°C at 760 mmHg

SMILES

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C1CNCCC1C2=NOC3=C2C=CC(=C3)F

InChI

InChI=1S/C12H13FN2O/c13-9-1-2-10-11(7-9)16-15-12(10)8-3-5-14-6-4-8/h1-2,7-8,14H,3-6H2

InChIKey

MRMGJMGHPJZSAE-UHFFFAOYSA-N

LogP

2.4339000000000004

Topological Polar Surface Area

38.06 Å²

Hydrogen Bond Donor/Acceptor

1 / 3

Complexity

245

Safety Information

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Hazard Statement

H301 Toxic if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

6-fluoro-3-piperidine-4-yl-benzo[d]isoxazole
AC-3455
6-fluoro-3-(4-piperidinyl)- 1,2-benzisoxazole
6-fluor-3-(4-piperidinyl)-1,2-benzisoxazole
6-fluoro-3-(4-piperidinyl)-1,2-benzisoxazol
Risperidone impurity M [EP]
4-(6-FLUOROBENZO[D]ISOXAZOL-3-YL)PIPERIDINE
MFCD03236724
6-fluoro-3-(4-piperidinyl)1,2 benzisoxazole
4-(6-Fluorobenzo(d)isoxazol-3-yl)piperidine
GF-0135
UNII-3911L280X6
6-Fluoro-3-piperid-4-yl-1,2-benzisoxazole
J-518714
6-fluoro-3-(4-piperidinyl)-1,2 -benzisoxazole
NS00116252
4-(6fluoro-1,2-benzisoxazol-3-yl)piperidine
6-fluoro-3-(4-piperidinyl)-1,2-benzoisoxazole
6-fluoro-3(4-piperidinyl)-1,2 benzisoxazole
6 -fluoro-3-(4-piperidinyl)-1,2-benzisoxazole
6-fluoro-3-(-4-piperidinyl)-1,2-benzisoxazole
Q27256839
3-(4-piperidinyl)-6-fluorobenzisoxazole
4-(6- fluoro-1,2-benzisoxazol-3-yl)piperidine
4-(6-fluoro-1,2- benzisoxazol-3-yl)piperidine
6-Fluoro-3-(4-piperidinyl)benzisoxazole, AldrichCPR
6-fluoro-3-piperidin-4-yl-1,2-benzoxazole
3-(4-PIPERIDINYL)-6-FLUOROBENZO[D]ISOXAZOLE
CHEMBL1668844
4-(6-fluoro-benzo[d]isoxazol-3-yl)-piperidine
4-(6-fluoro-1,2-benzisoxazol-3-yl)piperidine 84163-13-3

MDL Number

MFCD03236724

Customs Code

2934999090

FAQ

What regulatory guidelines apply to 6-Fluoro-3-(4-piperidinyl)-1,2-benzoxazole (CAS: 84163-77-9)?

6-Fluoro-3-(4-piperidinyl)-1,2-benzoxazole (CAS: 84163-77-9) falls under the scope of the GHS system, which includes classification for flammability, reactivity, and health hazards. It is also regulated under REACH in the European Union, requiring registration if produced or imported in quantities above 1 ton per year. In the U.S., the FDA and EPA have specific requirements for its use in pharmaceuticals and environmental impact assessment, respectively.

Are there alternatives to 6-Fluoro-3-(4-piperidinyl)-1,2-benzoxazole (CAS: 84163-77-9) in synthesis?

There are several alternatives to 6-Fluoro-3-(4-piperidinyl)-1,2-benzoxazole (CAS: 84163-77-9) in synthesis, including 6-Methyl-3-(4-piperidinyl)-1,2-benzoxazole and 6-Chloro-3-(4-piperidinyl)-1,2-benzoxazole, which can serve as structurally similar compounds. Other substitutes might include 1,2-Benzoxazole derivatives with different substituents, depending on the specific application.

What is the market or research trend for 6-Fluoro-3-(4-piperidinyl)-1,2-benzoxazole (CAS: 84163-77-9)?

The market for 6-Fluoro-3-(4-piperidinyl)-1,2-benzoxazole (CAS: 84163-77-9) is growing due to its potential in pharmaceutical applications, particularly as an intermediate in the synthesis of antiviral and antifungal drugs. Research trends are focusing on its biological activity, synthesis optimization, and environmental impact. Price trends are generally stable but may fluctuate based on supply and demand in the pharmaceutical industry.

How should waste containing 6-Fluoro-3-(4-piperidinyl)-1,2-benzoxazole (CAS: 84163-77-9) be handled?

Waste containing 6-Fluoro-3-(4-piperidinyl)-1,2-benzoxazole (CAS: 84163-77-9) should be collected in appropriate containers and stored in a secure, well-ventilated area. It should be disposed of according to local regulations, typically through incineration or other professional waste disposal methods. Environmental protection should be ensured by following best practices to minimize the risk of soil and water contamination.