(1S,3S,5S)-2-[(2S)-2-Amino-2-(3,5-dihydroxyadamantan-1-yl)acetyl]-2-azabicyclo[3.1.0]hexane-3-carbonitrile | CAS No. 841302-24-7

(1S,3S,5S)-2-[(2S)-2-Amino-2-(3,5-dihydroxyadamantan-1-yl)acetyl]-2-azabicyclo[3.1.0]hexane-3-carbonitrile

Basic Information

CAS Number

841302-24-7

Molecular Formula

C18H25N3O3

Molecular Weight

331.41 g/mol

AD

Basic Physical Properties

C1C2CC2N(C1C#N)C(=O)C(C34CC5CC(C3)(CC(C5)(C4)O)O)N

InChI

InChI=1S/C18H25N3O3/c19-6-12-1-11-2-13(11)21(12)15(22)14(20)16-3-10-4-17(23,7-16)9-18(24,5-10)8-16/h10-14,23-24H,1-5,7-9,20H2/t10?,11-,12+,13+,14-,16?,17?,18?/m1/s1

InChIKey

GAWUJFVQGSLSSZ-SZRCHTAPSA-N

LogP

0.91108

Complexity

652

Synonyms & References

English

  • UNII-PB91NV4HAN
  • 2-Azabicyclo(3.1.0)hexane-3-carbonitrile, 2-((2S)-2-amino-2-(3,5-dihydroxytricyclo(3.3.1.13,7)dec-1-yl)acetyl)-, (1S,3S,5S)-
  • (1S,3S,5S)-2-[(2S)-2-Amino-2-(3,5-dihydroxy-1-adamantyl)acetyl]-2-azabicyclo[3.1.0]hexane-3-carbonitrile
  • SCHEMBL13096265
  • BMS 510849
  • CHEBI:186991
  • PB91NV4HAN
  • Hydroxy Saxagliptin
  • PD045384
  • (S)-3,5-Dihydroxyadamantylglycine-L-cis-4,5-methanoprolinenitrile TFA salt
  • (1S,3S,5S)-2-((S)-2-amino-2-((1r,3R,5S,7S)-3,5-dihydroxyadamantan-1-yl)acetyl)-2-azabicyclo[3.1.0]hexane-3-carbonitrile
  • 5-Hydroxy saxagliptin
  • BDBM11543
  • (1S,3S,5S)-2-[(2S)-2-amino-2-(3,5-dihydroxyadamantan-1-yl)acetyl]-2-azabicyclo[3.1.0]hexane-3-carbonitrile; 2,2,2-trifluoroacetic acid
  • (1S,3S,5S)-2-((2S)-2-Amino-2-(3,5-dihydroxytricyclo(3.3.1.13,7)dec-1-yl)acetyl)-2-azabicyclo(3.1.0)hexane-3-carbonitrile
  • CHEMBL3350936
  • 841302-24-7
  • Saxagliptin metabolite M2
  • (1S,3S,5S)-2-[(2S)-2-aMino-2-(3,5-dihydroxytricyclo[3.3.1.13,7]dec-1-yl)acetyl]-2-Azabicyclo[3.1.0]hexane-3-carbonitrile
  • 5-Hydroxy Saxagliptin
  • (1S,3R,5S)-2-[(2S)-2-amino-2-[(3R,5S)-3,5-dihydroxy-1-adamantyl]acetyl]-2-azabicyclo[3.1.0]hexane-3-carbonitrile
  • 2-Azabicyclo[3.1.0]hexane-3-carbonitrile, 2-[(2S)-2-amino-2- (3,5-dihydroxytricyclo[3.3.1.13,7]dec-1-yl)acetyl]-, (1S,3...

MDL Number

MFCD19705094

FAQ

What regulatory guidelines apply to (1S,3S,5S)-2-[(2S)-2-Amino-2-(3,5-dihydroxyadamantan-1-yl)acetyl]-2-azabicyclo[3.1.0]hexane-3-carbonitrile (CAS: 841302-24-7)?

The compound (1S,3S,5S)-2-[(2S)-2-Amino-2-(3,5-dihydroxyadamantan-1-yl)acetyl]-2-azabicyclo[3.1.0]hexane-3-carbonitrile (CAS: 841302-24-7) is subject to various regulatory guidelines depending on its intended use. Under the Global Harmonized System (GHS), it may be classified as toxic or harmful based on its chemical properties. Additionally, it is regulated under REACH (Registration, Evaluation, Authorization and Restriction of Chemicals) in the European Union, requiring manufacturers and importers to register the substance with the European Chemicals Agency (ECHA). In the United States, the FDA (Food and Drug Administration) and EPA (Environmental Protection Agency) may also have specific requirements for handling and use of this substance.

Are there alternatives to (1S,3S,5S)-2-[(2S)-2-Amino-2-(3,5-dihydroxyadamantan-1-yl)acetyl]-2-azabicyclo[3.1.0]hexane-3-carbonitrile (CAS: 841302-24-7) in synthesis?

Yes, there are alternatives to (1S,3S,5S)-2-[(2S)-2-Amino-2-(3,5-dihydroxyadamantan-1-yl)acetyl]-2-azabicyclo[3.1.0]hexane-3-carbonitrile (CAS: 841302-24-7) in synthesis. Common alternatives include other amino acids or analogs with similar functional groups, such as 2-amino-2-(3,5-dihydroxyadamantan-1-yl)acetic acid. These alternatives can offer similar reactivity and can be used as intermediates in the synthesis of other bioactive compounds. Additionally, isomeric forms or other cyclic amine compounds may serve as viable substitutes.

What is the market or research trend for (1S,3S,5S)-2-[(2S)-2-Amino-2-(3,5-dihydroxyadamantan-1-yl)acetyl]-2-azabicyclo[3.1.0]hexane-3-carbonitrile (CAS: 841302-24-7)?

The market for (1S,3S,5S)-2-[(2S)-2-Amino-2-(3,5-dihydroxyadamantan-1-yl)acetyl]-2-azabicyclo[3.1.0]hexane-3-carbonitrile (CAS: 841302-24-7) is primarily driven by its applications in pharmaceutical and medicinal chemistry research. Recent research trends show increased interest in its potential as a precursor in the development of new drug candidates. Market trends indicate a growing demand for this compound as it continues to be explored for its biological activities and therapeutic potential. Additionally, its incorporation in the synthesis of complex natural products and bioactive molecules is also on the rise.

How should waste containing (1S,3S,5S)-2-[(2S)-2-Amino-2-(3,5-dihydroxyadamantan-1-yl)acetyl]-2-azabicyclo[3.1.0]hexane-3-carbonitrile (CAS: 841302-24-7) be handled?

Waste containing (1S,3S,5S)-2-[(2S)-2-Amino-2-(3,5-dihydroxyadamantan-1-yl)acetyl]-2-azabicyclo[3.1.0]hexane-3-carbonitrile (CAS: 841302-24-7) should be handled according to local and national regulations. Waste management practices should include proper collection and segregation of the waste. For liquid waste, it should be stored in appropriate containers and disposed of through incineration or professional waste disposal services. Environmental protection precautions must be taken to prevent contamination of soil and water. It is recommended to consult with environmental health and safety (EHS) professionals for guidance on specific disposal methods and to ensure compliance with all regulations.

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