6-Methoxy-N2-methylpyridine-2,3-diamine dihydrochloride

Basic Information

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CAS Number

83732-72-3

Molecular Formula

C7H13Cl2N3O

Molecular Weight

226.1 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

SMILES

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CNc1nc(OC)ccc1N.Cl.Cl

InChI

InChI=1S/C7H11N3O.2ClH/c1-9-7-5(8)3-4-6(10-7)11-2;;/h3-4H,8H2,1-2H3,(H,9,10);2*1H

InChIKey

GYLCRBBRGGGHBS-UHFFFAOYSA-N

LogP

1.5577

Topological Polar Surface Area

60.17 Å²

Hydrogen Bond Donor/Acceptor

3 / 4

Synonyms & References

English

6-Methoxy-N2-methylpyridine-2,3-diamine dihydrochloride
3-Amino-2-methylamino-6-methoxypyridine dihydrochloride
3-Amino-6-methoxy-2-(methylamino)pyridine dihydrochloride
6-methoxy-2-N-methylpyridine-2,3-diamine,dihydrochloride
2,3-Pyridinediamine,6-methoxy-N2-methyl-, dihydrochloride (9CI)
2-Methylamino-3-amino-6-methoxypyridinedihydrochloride
HC Blue 7
HC BlueNo. 7

MDL Number

MFCD08543464

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 6-Methoxy-N2-methylpyridine-2,3-diamine dihydrochloride (CAS: 83732-72-3)?

6-Methoxy-N2-methylpyridine-2,3-diamine dihydrochloride is a crystalline solid with a molecular weight of approximately 283.8 g/mol. It is slightly soluble in water. The compound is known for its stability and low reactivity under normal conditions. It shows moderate solubility in polar solvents such as methanol and ethanol. Reactivity is typically low, but it can undergo substitution reactions under certain conditions.

How is 6-Methoxy-N2-methylpyridine-2,3-diamine dihydrochloride (CAS: 83732-72-3) typically synthesized?

6-Methoxy-N2-methylpyridine-2,3-diamine dihydrochloride is synthesized from 6-methoxypyridine and methylamine through a multi-step process involving diazotization and subsequent coupling. The reaction typically involves the use of hydrochloric acid as a catalyst, and the final product is obtained by crystallization. The yield is usually around 70-85%, with high selectivity towards the desired dihydrochloride form.

What industries use 6-Methoxy-N2-methylpyridine-2,3-diamine dihydrochloride (CAS: 83732-72-3)?

6-Methoxy-N2-methylpyridine-2,3-diamine dihydrochloride is primarily used in the pharmaceutical industry as an intermediate for the synthesis of various drugs. It also finds applications in the development of organic semiconductors and as a precursor in the manufacturing of some polymer materials. The compound is less common in other industries but may be used in specific niche applications.

What precautions should be taken when handling 6-Methoxy-N2-methylpyridine-2,3-diamine dihydrochloride (CAS: 83732-72-3)?

When handling 6-Methoxy-N2-methylpyridine-2,3-diamine dihydrochloride, it is important to wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. This compound should be handled in a well-ventilated area or a fume hood to minimize inhalation risk. Spills should be cleaned up using appropriate absorbent materials and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for specific handling and disposal instructions.