4-(Trifluoromethyl)benzenesulfonamide

Basic Information

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CAS Number

830-43-3

Molecular Formula

C7H6F3NO2S

Molecular Weight

225.19 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

179.0 to 183.0 deg-C

Boiling Point

304.8 ºC at 760 mmHg

Density

1.482

Flash Point

138.1℃

Refractive Index

1.493

SMILES

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C1=CC(=CC=C1C(F)(F)F)S(=O)(=O)N

InChI

InChI=1S/C7H6F3NO2S/c8-7(9,10)5-1-3-6(4-2-5)14(11,12)13/h1-4H,(H2,11,12,13)

InChIKey

TVHXQQJDMHKGGK-UHFFFAOYSA-N

LogP

1.3528000000000002

Topological Polar Surface Area

60.160000000000004 Å²

Hydrogen Bond Donor/Acceptor

2 / 3

Complexity

285

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

p-(Trifluoromethyl)benzenesulfonamide
CS-0097815
FS-1347
4-(Trifluoromethyl)benzenesulfonamide #
4-(trifluoromethyl) benzenesulfonamide
BRN 2695323
AM20060959
4-(Trifluoromethyl)benzenesulfonamide
J-513917
4-trifluoromethyl-benzenesulfonamide
4-(trifluoromethyl)benzene-1-sulfonamide
Benzenesulfonamide, 4-(trifluoromethyl)-
SY013481
FT-0616912
NS00042499
SCHEMBL792636
T2847
Benzenesulfonamide, p-(trifluoromethyl)-
4-trifluoromethylbenzene sulfonamide
4-(trifluoromethyl)-benzene sulfonamide
4-trifluoromethylbenzenesulfonamide
4-(trifluoromethyl)-benzenesulfonamide
EINECS 212-596-1
AKOS000141373
SB80409
p-Trifluoromethylbenzene sulfonamide
p-trifluoromethylbenzenesulfonamide
830-43-3
O11107
MFCD00159251
alpha,alpha,alpha-trifluoro-p-toluenesulfonamide

MDL Number

MFCD00159251

Customs Code

2935009090

FAQ

What regulatory guidelines apply to 4-(Trifluoromethyl)benzenesulfonamide (CAS: 830-43-3)?

4-(Trifluoromethyl)benzenesulfonamide (CAS: 830-43-3) falls under various regulatory guidelines including GHS (Global Harmonized System of Classification and Labeling of Chemicals) for classification as a hazardous substance. It must comply with REACH regulations in the European Union, which requires registration based on its properties. FDA and EPA regulations in the United States may also apply, depending on its use in pharmaceuticals, pesticides, or industrial applications.

Are there alternatives to 4-(Trifluoromethyl)benzenesulfonamide (CAS: 830-43-3) in synthesis?

Alternatives to 4-(Trifluoromethyl)benzenesulfonamide include other sulfonamides and trifluoromethylated compounds. These can be used as reagents in similar reactions. Common substitutes may include trifluoromethylbenzenesulfonate or other trifluoromethyl sulfonamides, depending on the specific application and desired properties.

What is the market or research trend for 4-(Trifluoromethyl)benzenesulfonamide (CAS: 830-43-3)?

The market trend for 4-(Trifluoromethyl)benzenesulfonamide (CAS: 830-43-3) is driven by its use in pharmaceuticals and fine chemicals, particularly in the development of new drugs. Research is focusing on its potential in medicinal chemistry and as a building block for organic synthesis. The increasing interest in trifluoromethylated compounds due to their unique biological properties is also a key trend.

How should waste containing 4-(Trifluoromethyl)benzenesulfonamide (CAS: 830-43-3) be handled?

Waste containing 4-(Trifluoromethyl)benzenesulfonamide (CAS: 830-43-3) should be collected in appropriate containers and disposed of through a professional waste disposal service. Incineration is a common method, but it must be conducted under controlled conditions to minimize environmental impact. Environmental precautions include ensuring no release into waterways and proper handling to prevent exposure to personnel and the environment.