1-[4-(Chloromethyl)-1,3-thiazol-2-yl]-N,N-dimethylmethanamine hydrochloride (1:1) | CAS No. 82586-71-8

1-[4-(Chloromethyl)-1,3-thiazol-2-yl]-N,N-dimethylmethanamine hydrochloride (1:1)

Basic Information

CAS Number

82586-71-8

Molecular Formula

C7H12Cl2N2S

Molecular Weight

190.7 g/mol

AD

Basic Physical Properties

CN(CC1=NC(CCl)=CS1)C

InChI

InChI=1S/C7H11ClN2S/c1-10(2)4-7-9-6(3-8)5-11-7/h5H,3-4H2,1-2H3

InChIKey

BUDMJAMXOTXJAA-UHFFFAOYSA-N

LogP

1.9435

Topological Polar Surface Area

16.130000000000003 Ų

Hydrogen Bond Donor/Acceptor

0 / 2

Complexity

121

Synonyms & References

English

  • 2-Dimethyl amino methyl-4-chloro methyl thiazole HCl
  • 1-[4-(chloromethyl)-1,3-thiazol-2-yl]-N,N-dimethylmethanamine,hydrochloride
  • 4-(chloromethyl)-N,N-dimethyl-2-Thiazolemethanamine hydrochloride
  • N-{[4-(chloromethyl)-1,3-thiazol-2-yl]methyl}-N,N-dimethylamine hydrochloride
  • N-{[4-(chloromethyl)-1,3-thiazol-2-yl)methyl}-N,N-dimethylamine hydrochloride
  • VJJZXQCIDAQYNQ-UHFFFAOYSA-N
  • 2-Dimethyl amino methyl-4-chloro methyl thiazole H
  • 2-dimethylaminomethyl-4-thiazolylmethylchloride hydrochloride
  • 4-Chloromethyl-2-dimethylaminomethylthiazole, hydrochloride
  • 1-(4-(chloromethyl)thiazol-2-yl)-N,N-dimethylmethanamine hydrochlo

MDL Number

MFCD07787539

FAQ

What are the physical and chemical properties of 1-[4-(Chloromethyl)-1,3-thiazol-2-yl]-N,N-dimethylmethanamine hydrochloride (CAS: 82586-71-8)?

This compound is a white crystalline solid with a molecular weight of approximately 337.66 g/mol. It has a high solubility in water and moderate solubility in organic solvents. Chemically, it is stable but reacts with strong bases to form the corresponding base. The compound is also sensitive to moisture and should be stored in a dry environment.

How is 1-[4-(Chloromethyl)-1,3-thiazol-2-yl]-N,N-dimethylmethanamine hydrochloride (CAS: 82586-71-8) typically synthesized?

This compound can be synthesized through multistep reactions involving thiazole derivatives and dimethylamine. A common approach involves the chloromethylation of thiazole, followed by a nucleophilic substitution reaction with dimethylamine. The reaction is typically conducted under mild conditions and often requires the use of a catalyst or reagent to improve yield and selectivity.

What industries use 1-[4-(Chloromethyl)-1,3-thiazol-2-yl]-N,N-dimethylmethanamine hydrochloride (CAS: 82586-71-8)?

This compound finds applications in the pharmaceutical industry for its biological activity, as well as in the sensor and semiconductor industries due to its unique electronic properties. It is also used in the polymer industry for modifying the properties of certain materials.

What precautions should be taken when handling 1-[4-(Chloromethyl)-1,3-thiazol-2-yl]-N,N-dimethylmethanamine hydrochloride (CAS: 82586-71-8)?

When handling this compound, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or fume hood to minimize inhalation risks. Spills should be immediately cleaned up using appropriate absorbents, and the material safety data sheet (MSDS) should be consulted for specific disposal instructions. Always ensure proper storage conditions to prevent moisture absorption and degradation.

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