N~2~-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-{15-oxo-19-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]-4,7,10-trioxa-14-azanonadec-1-yl}-L-glutamine | CAS No. 817169-73-6

N~2~-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-{15-oxo-19-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]-4,7,10-trioxa-14-azanonadec-1-yl}-L-glutamine

Basic Information

CAS Number

817169-73-6

Molecular Formula

C40H55N5O10S

Molecular Weight

797.97 g/mol

AD

Basic Physical Properties

OC(=O)[C@H](CCC(=O)NCCCOCCOCCOCCCNC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12)NC(=O)OCC1C2=CC=CC=C2C2=C1C=CC=C2

InChI

InChI=1S/C40H55N5O10S/c46-35(14-6-5-13-34-37-33(26-56-34)43-39(50)45-37)41-17-7-19-52-21-23-54-24-22-53-20-8-18-42-36(47)16-15-32(38(48)49)44-40(51)55-25-31-29-11-3-1-9-27(29)28-10-2-4-12-30(28)31/h1-4,9-12,31-34,37H,5-8,13-26H2,(H,41,46)(H,42,47)(H,44,51)(H,48,49)(H2,43,45,50)/t32-,33-,34-,37-/m0/s1

InChIKey

MGOWNVYDCIBVKC-FNHRVDEZSA-N

LogP

3.5467000000000066

Topological Polar Surface Area

202.64999999999998 Ų

Hydrogen Bond Donor/Acceptor

6 / 15

Complexity

1240

Synonyms & References

English

  • FMOC-GLN(BIOTINYL-PEG)-OH
  • Fmoc-glu(biotinyl-peg)-oh
  • (2S)-5-[3-[2-[2-[3-[5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoylamino]propoxy]ethoxy]ethoxy]propylamino]-2-(9H-fluoren-9-ylmethoxycarbonylamino)-5-oxopentanoic aci
  • N-α-Fmoc-N-γ-(N-biotinyl-3-(2-(2-(3-aminopropyloxy)ethoxy)ethoxy)propyl)-L-glutamine
  • C40H55N5O10S
  • 6886AH
  • Fmoc-Glu(biotinyl-PEG)-OH

MDL Number

MFCD18782826

FAQ

What are the physical and chemical properties of N~2~-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-{15-oxo-19-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]-4,7,10-trioxa-14-azanonadec-1-yl}-L-glutamine (CAS: 817169-73-6)?

N~2~-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-{15-oxo-19-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]-4,7,10-trioxa-14-azanonadec-1-yl}-L-glutamine is a crystalline compound with a high molecular weight and poor water solubility. It is highly reactive due to its functional groups. The compound is stable under normal conditions but decomposes upon exposure to heat or strong acids. It is soluble in organic solvents such as DMSO and acetonitrile.

How is N~2~-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-{15-oxo-19-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]-4,7,10-trioxa-14-azanonadec-1-yl}-L-glutamine (CAS: 817169-73-6) typically synthesized?

N~2~-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-{15-oxo-19-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]-4,7,10-trioxa-14-azanonadec-1-yl}-L-glutamine is synthesized through multi-step peptide synthesis followed by coupling with the fluoren-9-ylmethoxy carbonyl group. The synthesis involves careful selection of protecting groups and the use of appropriate solvents and catalysts to ensure high yield and selectivity.

What industries use N~2~-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-{15-oxo-19-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]-4,7,10-trioxa-14-azanonadec-1-yl}-L-glutamine (CAS: 817169-73-6)?

N~2~-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-{15-oxo-19-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]-4,7,10-trioxa-14-azanonadec-1-yl}-L-glutamine is primarily used in the pharmaceutical industry for the development of new drugs and in the research of protein-protein interactions. It is also of interest in polymer science for its potential use in the synthesis of functional polymers and in semiconductor technology for its electronic properties.

What precautions should be taken when handling N~2~-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-{15-oxo-19-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]-4,7,10-trioxa-14-azanonadec-1-yl}-L-glutamine (CAS: 817169-73-6)?

When handling N~2~-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-{15-oxo-19-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]-4,7,10-trioxa-14-azanonadec-1-yl}-L-glutamine, it is important to wear appropriate personal protective equipment (PPE), including gloves, safety glasses, and a lab coat. The compound should be handled in a well-ventilated area or a fume hood to prevent inhalation. In case of a spill, it should be carefully cleaned up using appropriate procedures and materials. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.

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