N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenyl-methoxy]methyl]-3-[tert-butyl(dimethyl)silyl]oxy-4-hydroxy-tetrahydrofuran-2-yl]purin-6-yl]benzamide

Basic Information

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CAS Number

81265-93-2

Molecular Formula

C44H49N5O7Si

Molecular Weight

787.99 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Density

1.23±0.1 g/cm3 (20 ºC 760 Torr),

Solubility

Insuluble (1.1E-6 g/L) (25 ºC),

SMILES

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O=C(NC1=C2N=CN([C@@H]3O[C@H](COC(C4=CC=C(OC)C=C4)(C5=CC=C(OC)C=C5)C6=CC=CC=C6)[C@@H](O)[C@H]3O[Si](C)(C(C)(C)C)C)C2=NC=N1)C7=CC=CC=C7

InChI

InChI=1S/C44H49N5O7Si/c1-43(2,3)57(6,7)56-38-37(50)35(55-42(38)49-28-47-36-39(45-27-46-40(36)49)48-41(51)29-14-10-8-11-15-29)26-54-44(30-16-12-9-13-17-30,31-18-22-33(52-4)23-19-31)32-20-24-34(53-5)25-21-32/h8-25,27-28,35,37-38,42,50H,26H2,1-7H3,(H,45,46,48,51)/t35-,37-,38-,42-/m1/s1

InChIKey

DAZIGOPASNJPCJ-GNECSJIWSA-N

LogP

7.753200000000009

Topological Polar Surface Area

139.08000000000004 Å²

Hydrogen Bond Donor/Acceptor

2 / 12

Complexity

1250

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H332 Harmful if inhaled
Acute toxicity, inhalation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

5'-O-DMT-2'-O-TBDMS-N-Bz-Adenosine
5’-DMT-2’-TBDMS-Bz-rA
5'-DMT-2'-TBDMS-BZ-RA
N-(9-((2R,3R,4R,5R)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-((tert-but ldimethylsilyl)oxy)-4-hydroxytetrahydr...
N-(9-((2R,3R,4R,5R)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-((tert-butyldimethylsilyl)oxy)-4-hydroxytetrahydrofuran-2-yl)-9H-purin-6-yl)benzamide
N6-BENZOYL-2'-O-TERT-BUTYLDIMETHYLSILYL-5'-O-DMT-ADENOSINE
N6-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-(tert-butyldimethylsilyl)adenosine
C44H49N5O7Si
N-Benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]adenosine
2621AC
SB18252

MDL Number

MFCD00080294

FAQ

What regulatory guidelines apply to N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenyl-methoxy]methyl]-3-[tert-butyl(dimethyl)silyl]oxy-4-hydroxy-tetrahydrofuran-2-yl]purin-6-yl]benzamide (CAS: 81265-93-2)?

N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenyl-methoxy]methyl]-3-[tert-butyl(dimethyl)silyl]oxy-4-hydroxy-tetrahydrofuran-2-yl]purin-6-yl]benzamide (CAS: 81265-93-2) is subject to GHS classification, REACH regulations, and FDA/EPA requirements. It should be handled according to these guidelines to ensure safe and compliant use in industrial and research settings.

Are there alternatives to N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenyl-methoxy]methyl]-3-[tert-butyl(dimethyl)silyl]oxy-4-hydroxy-tetrahydrofuran-2-yl]purin-6-yl]benzamide (CAS: 81265-93-2) in synthesis?

While N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenyl-methoxy]methyl]-3-[tert-butyl(dimethyl)silyl]oxy-4-hydroxy-tetrahydrofuran-2-yl]purin-6-yl]benzamide (CAS: 81265-93-2) is a specific compound, alternatives such as related purines or benzamides may be used in synthesis. Common alternative reagents and substitutes include purine derivatives and other benzamide analogs.

What is the market or research trend for N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenyl-methoxy]methyl]-3-[tert-butyl(dimethyl)silyl]oxy-4-hydroxy-tetrahydrofuran-2-yl]purin-6-yl]benzamide (CAS: 81265-93-2)?

The market for N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenyl-methoxy]methyl]-3-[tert-butyl(dimethyl)silyl]oxy-4-hydroxy-tetrahydrofuran-2-yl]purin-6-yl]benzamide (CAS: 81265-93-2) is primarily driven by its use in research and specialized pharmaceutical applications. Emerging trends include its application in drug discovery and personalized medicine. Price trends and demand are closely linked to advancements in these fields.

How should waste containing N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenyl-methoxy]methyl]-3-[tert-butyl(dimethyl)silyl]oxy-4-hydroxy-tetrahydrofuran-2-yl]purin-6-yl]benzamide (CAS: 81265-93-2) be handled?

Waste containing N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenyl-methoxy]methyl]-3-[tert-butyl(dimethyl)silyl]oxy-4-hydroxy-tetrahydrofuran-2-yl]purin-6-yl]benzamide (CAS: 81265-93-2) should be collected and disposed of according to hazardous waste regulations. Proper incineration or professional waste disposal services should be used. Ensure all environmental protection precautions are followed to minimize environmental impact.