N-Formyl-methionyl-leucyl-phenylalanyl-phenylalanine

Basic Information

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CAS Number

8016-84-0

Molecular Formula

C30H40N4O6S

Molecular Weight

584.73 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Density

0.886 g/mL at 25 °C

Refractive Index

n20/D 1.481

SMILES

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S(C)CC[C@@H](C(N[C@H](C(N[C@H](C(N[C@H](C(=O)O)CC1C=CC=CC=1)=O)CC1C=CC=CC=1)=O)CC(C)C)=O)NC=O

InChI

1S/C30H40N4O6S/c1-20(2)16-24(32-27(36)23(31-19-35)14-15-41-3)28(37)33-25(17-21-10-6-4-7-11-21)29(38)34-26(30(39)40)18-22-12-8-5-9-13-22/h4-13,19-20,23-26H,14-18H2,1-3H3,(H,31,35)(H,32,36)(H,33,37)(H,34,38)(H,39,40)/t23-,24-,25-,26-/m0/s1

InChIKey

PJENNOWAVBNNNE-CQJMVLFOSA-N

LogP

1.924600000000003

Topological Polar Surface Area

153.7 Å²

Hydrogen Bond Donor/Acceptor

5 / 10

Complexity

845

Safety Information

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Hazard Statement

H226 Flammable liquid and vapor
Flammable liquids

H304 May be fatal if swallowed and enters airways
Aspiration hazard

H315 Causes skin irritation
Skin corrosion/irritation

H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled
Sensitization, respiratory

H400 Very toxic to aquatic life
Hazardous to the aquatic environment, acute hazard

Synonyms & References

English

Tagetes Oil
TAGETES OIL(MARIGOLD OIL)
Tagette oil
Cydonia oil
FEMA No. 3040
Marigold absolute (Tageta minuta)
Oil of Tagetes glandulifera
Oils, betaagetes
Oils, Tagetes
Taget oil
Tagetes absolute
Tagetes oil (Tagetes spp.)
FOR-MET-LEU-PHE-PHE-OH
f-Met-leu-phe-phe
N-Formyl-methionyl-leucyl-phenylalanyl-phenylalanine
(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-formamido-4-methylsulfanylbutanoyl]amino]-4-methylpentanoyl]amino]-3-phenylpropanoyl]amino]-3-phenylpropanoic acid
fMLPP
fMLFF
N-(N-(N-(N-Formyl-L-methionyl)-L-leucyl)-L-phenylalanyl)-L-phenylalanine
N-formyl-L-methionyl-L-leucyl-L-phenylalanyl-L-phenylalanine
L-Phenylalanine, N-(N-(N-(N-formyl-L-methio

FAQ

What is N-Formyl-methionyl-leucyl-phenylalanyl-phenylalanine (CAS: 8016-84-0)?

N-Formyl-methionyl-leucyl-phenylalanyl-phenylalanine, also known as FMLPP, is a synthetic peptide used extensively in biological research. It is a tetrapeptide with a formyl group attached to the N-terminus. This compound is often used as a pharmacological tool in studies of cell signaling pathways and receptor interactions.

What are the main uses of N-Formyl-methionyl-leucyl-phenylalanyl-phenylalanine (CAS: 8016-84-0)?

N-Formyl-methionyl-leucyl-phenylalanyl-phenylalanine (FMLPP) is primarily used in research for studying G-protein coupled receptors (GPCRs), particularly to activate the Gq/11 family of GPCRs. It is also used in cell biology to investigate signaling pathways and to modulate various cellular processes.

Is N-Formyl-methionyl-leucyl-phenylalanyl-phenylalanine (CAS: 8016-84-0) safe?

N-Formyl-methionyl-leucyl-phenylalanyl-phenylalanine (FMLPP) is generally considered safe for research use when handled properly. However, it should be used under appropriate laboratory conditions, with proper protective equipment to avoid direct skin contact and inhalation. It should be stored in a cool, dark place away from direct sunlight and flammable materials.

How should N-Formyl-methionyl-leucyl-phenylalanyl-phenylalanine (CAS: 8016-84-0) be stored?

N-Formyl-methionyl-leucyl-phenylalanyl-phenylalanine (FMLPP) should be stored in a cool, dry place, away from direct sunlight and heat sources. It is recommended to keep it in a tightly sealed container to prevent degradation. The compound should be stored at room temperature or below (2-8°C) for optimal stability and to minimize the risk of contamination.