1-[5-O-(Anilino{2-[(2,2-dimethylpropanoyl)sulfanyl]ethoxy}phosphoryl)-3-azido-2,3-dideoxypentofuranosyl]-5-methyl-2,4(1H,3H)-pyrimidinedione | CAS No. 8016-38-4

1-[5-O-(Anilino{2-[(2,2-dimethylpropanoyl)sulfanyl]ethoxy}phosphoryl)-3-azido-2,3-dideoxypentofuranosyl]-5-methyl-2,4(1H,3H)-pyrimidinedione

Basic Information

CAS Number

8016-38-4

Molecular Formula

C23H31N6O7PS

Molecular Weight

527.5 g/mol

AD

Basic Physical Properties

Boiling Point

163 °C

Density

0.868 g/mL at 25 °C

Flash Point

70 °C

Refractive Index

n20/D 1.47(lit.)

CC1CN(CC(C1(C)O)N)C2=C3CCC(C3=NC=C2NC(=O)C4=NC(=C(C=C4)F)C5=C(C=CC=C5F)F)O

InChI

InChI=1S/C23H31N6O7PS/c1-15-13-29(22(32)25-20(15)30)19-12-17(26-28-24)18(36-19)14-35-37(33,27-16-8-6-5-7-9-16)34-10-11-38-21(31)23(2,3)4/h5-9,13,17-19H,10-12,14H2,1-4H3,(H,27,33)(H,25,30,32)

InChIKey

ZLSOBBKZHHOXAY-UHFFFAOYSA-N

Complexity

849

Synonyms & References

English

  • SCHEMBL15872607
  • 8016-38-4
  • US10517858, Example 63 (Diastereoisomer 2)
  • 1381930-10-4
  • FEMA 2771
  • nerolibigaradeoil,tunisian
  • nerolioil,tunisian
  • Oils,neroli
  • Orangeblossomoil
  • Orangeflowerconcrete
  • CITRUS AURANTIUM
  • SWEET ORANGE OIL
  • NEROLI
  • Neroli oil, Morocco
  • Orange essential oil
  • Orange essential oil​​

FAQ

What regulatory guidelines apply to 1-[5-O-(Anilino{2-[(2,2-dimethylpropanoyl)sulfanyl]ethoxy}phosphoryl)-3-azido-2,3-dideoxypentofuranosyl]-5-methyl-2,4(1H,3H)-pyrimidinedione (CAS: 8016-38-4)?

The compound 1-[5-O-(Anilino{2-[(2,2-dimethylpropanoyl)sulfanyl]ethoxy}phosphoryl)-3-azido-2,3-dideoxypentofuranosyl]-5-methyl-2,4(1H,3H)-pyrimidinedione (CAS: 8016-38-4) is subject to regulatory guidelines such as REACH in Europe, which requires registration for substances above one tonne per year. It is also regulated under the U.S. FDA for pharmaceutical applications and the EPA for environmental hazards. Ensure compliance with local laws and guidelines for handling, storage, and disposal.

Are there alternatives to 1-[5-O-(Anilino{2-[(2,2-dimethylpropanoyl)sulfanyl]ethoxy}phosphoryl)-3-azido-2,3-dideoxypentofuranosyl]-5-methyl-2,4(1H,3H)-pyrimidinedione (CAS: 8016-38-4) in synthesis?

Alternatives to 1-[5-O-(Anilino{2-[(2,2-dimethylpropanoyl)sulfanyl]ethoxy}phosphoryl)-3-azido-2,3-dideoxypentofuranosyl]-5-methyl-2,4(1H,3H)-pyrimidinedione include other nucleosides and analogs such as 2′-deoxyuridine and 2′-deoxyguanosine. Researchers may also explore synthetic pathways using isomers or reagents like 2′-deoxythymidine monophosphate as substitutes, depending on the specific application requirements.

What is the market or research trend for 1-[5-O-(Anilino{2-[(2,2-dimethylpropanoyl)sulfanyl]ethoxy}phosphoryl)-3-azido-2,3-dideoxypentofuranosyl]-5-methyl-2,4(1H,3H)-pyrimidinedione (CAS: 8016-38-4)?

The market for 1-[5-O-(Anilino{2-[(2,2-dimethylpropanoyl)sulfanyl]ethoxy}phosphoryl)-3-azido-2,3-dideoxypentofuranosyl]-5-methyl-2,4(1H,3H)-pyrimidinedione (CAS: 8016-38-4) is driven by its use in antiviral drug development, particularly in the treatment of HIV. Research trends focus on improving its efficacy and stability, as well as exploring its applications in combination therapies and novel drug delivery systems.

How should waste containing 1-[5-O-(Anilino{2-[(2,2-dimethylpropanoyl)sulfanyl]ethoxy}phosphoryl)-3-azido-2,3-dideoxypentofuranosyl]-5-methyl-2,4(1H,3H)-pyrimidinedione (CAS: 8016-38-4) be handled?

Waste containing 1-[5-O-(Anilino{2-[(2,2-dimethylpropanoyl)sulfanyl]ethoxy}phosphoryl)-3-azido-2,3-dideoxypentofuranosyl]-5-methyl-2,4(1H,3H)-pyrimidinedione (CAS: 8016-38-4) should be collected in appropriate containers and stored in a secure environment. Incineration or professional waste disposal is recommended for safe disposal. Follow local environmental protection guidelines and ensure all disposal methods comply with regulatory standards to minimize environmental impact.

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