![N-[(3S)-1-(Dimethylcarbamoyl)-3-pyrrolidinyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide structure](https://static.chemtradehub.com/structs/101/1013920-15-4-a4c8.webp "N-[(3S)-1-(Dimethylcarbamoyl)-3-pyrrolidinyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide structure")
N-[(3S)-1-(Dimethylcarbamoyl)-3-pyrrolidinyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide
CAS Number:
1013920-15-4
Molecular Formula:
C23H26FN5O3
(1R,4S)-4-(3,4-Dichlorophenyl)-N-methyl-1,2,3,4-tetrahydro-1-naphthalenamine hydrochloride (1:1) | CAS No. 79617-99-5
(1R,4S)-4-(3,4-Dichlorophenyl)-N-methyl-1,2,3,4-tetrahydro-1-naphthalenamine hydrochloride (1:1)
Basic Information
CAS Number
79617-99-5
Molecular Formula
C17H18Cl3N
Molecular Weight
342.7 g/mol
AD
Basic Physical Properties
Melting Point
275-277°C
Boiling Point
443.8 °C at 760 mmHg
Flash Point
222.2 °C
Synonyms & References
English
- Sertraline basis
- Seraline
- 4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-naphthalenimine hydrochloride
- 4-(3,4-Dichlorophenyl)-1,2,3,4-Tetrahydro-N-Methyl-1-naphthalenaminehydrochlroide
- SERTRALINE RACEMATE HCl
- (+)-cis-N-Methyl-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthalenamine hyd
- Sertraline hydrechloride
- 4-(3,4-DICHLOROPHENYL)-1,2,3,4-TETRAHYDRO-N-METHYL-1-NAPHTHALENAMINE HCL
- 4-(3,4-DICHLOROPHENYL)-1,2,3,4-TETRAHYDRO-N-METHYL-1-NAPHTHALENAMINEHYDROCHLORIDE
- cis-N-Methyl-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthalenamine hydrochloride
- 4-(3,4-DICHLOROPHENYL)-1,2,3,4-TETRAHYDRO-N-METHYL-1-NAPTHALENAMINE
- 4-(3,4-DICHLOROPHENYL)-1,2,3,4-TETRAHYDRO-N-METHYL-1-NAPHTHALENIMINECHLORIDE
- RACEMIC SERTRALINE HYDROCHLORIDE
- CIS-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-n-methyl-1-naphthalenamine hcl
- Sertraline Racemate
- intermediate of sertraline
- sertraline intermediate
- 4-(3,4-dichlorophenyl)-N-methyl-3,4-dihydro-2H-naphthalen-1-imine,hydrochloride
- (1S*,2S*)-2-phenylcyclohexanol
- (1S*,4R*)-trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-napthalenamine hydrochloride
- 2-PHENYL-CYCLOHEXANOL(CIS)
- cis-2-phenyl-1-cyclohexanol
- cis-2-phenylcyclohexan-1-ol
- cis-2-phenyl-cyclohexanol
- trans-2-phenylcyclohexanol
- trans-N-methyl-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthalenamine hydrochloride
- 1R,4S)-rel-4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-naphthalenamine hydrochloride
- (1R,4S)-rel-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine
- hydrochloride (1:1)
MDL Number
MFCD09025656
FAQ
What are the physical and chemical properties of (1R,4S)-4-(3,4-Dichlorophenyl)-N-methyl-1,2,3,4-tetrahydro-1-naphthalenamine hydrochloride (CAS: 79617-99-5)?
(1R,4S)-4-(3,4-Dichlorophenyl)-N-methyl-1,2,3,4-tetrahydro-1-naphthalenamine hydrochloride is a white crystalline solid. Its molecular weight is approximately 336.1 g/mol. It has a solubility of about 1.3 g/L in water and is moderately soluble in common organic solvents. The compound reacts with bases and is stable under normal storage conditions. It is not flammable but can decompose at high temperatures, releasing toxic fumes.
How is (1R,4S)-4-(3,4-Dichlorophenyl)-N-methyl-1,2,3,4-tetrahydro-1-naphthalenamine hydrochloride (CAS: 79617-99-5) typically synthesized?
(1R,4S)-4-(3,4-Dichlorophenyl)-N-methyl-1,2,3,4-tetrahydro-1-naphthalenamine hydrochloride is synthesized via a multi-step process involving the coupling of a 3,4-dichloroaniline derivative and a substituted naphthalene, followed by hydrogenation and hydrochloric acid treatment. The process is carried out under mild conditions to ensure high yield and selectivity.
What industries use (1R,4S)-4-(3,4-Dichlorophenyl)-N-methyl-1,2,3,4-tetrahydro-1-naphthalenamine hydrochloride (CAS: 79617-99-5)?
(1R,4S)-4-(3,4-Dichlorophenyl)-N-methyl-1,2,3,4-tetrahydro-1-naphthalenamine hydrochloride is used in the pharmaceutical industry for developing certain types of analgesics and anti-inflammatory drugs. It is also utilized in the polymer industry for modifying material properties and in the semiconductor industry for enhanced conductivity and stability.
What precautions should be taken when handling (1R,4S)-4-(3,4-Dichlorophenyl)-N-methyl-1,2,3,4-tetrahydro-1-naphthalenamine hydrochloride (CAS: 79617-99-5)?
When handling (1R,4S)-4-(3,4-Dichlorophenyl)-N-methyl-1,2,3,4-tetrahydro-1-naphthalenamine hydrochloride, use appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Store in a cool, dry place away from direct sunlight and heat sources. Use in a well-ventilated area or fume hood to avoid inhalation of fumes. In case of spill, neutralize with appropriate absorbent materials and dispose of according to local regulations. Refer to the Safety Data Sheet (SDS) for detailed information.
Related Compounds
![7-Methylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid structure](https://static.chemtradehub.com/structs/101/1016505-59-1-4c54.webp "7-Methylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid structure")
7-Methylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid
CAS Number:
1016505-59-1
Molecular Formula:
C8H7N3O2
![2-Fluoro-6-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)benzoic acid structure](https://static.chemtradehub.com/structs/104/1048919-15-8-ba81.webp "2-Fluoro-6-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)benzoic acid structure")
2-Fluoro-6-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)benzoic acid
CAS Number:
1048919-15-8
Molecular Formula:
C12H14FNO4
1,5,8-Trihydroxy-3-methoxy-2-(3-methyl-2-buten-1-yl)-9H-xanthen-9-one
CAS Number:
110187-11-6
Molecular Formula:
C19H18O6
![9-Benzyl-2,9-diazaspiro[5.5]undecane dihydrochloride structure](https://static.chemtradehub.com/structs/119/1198286-24-6-4781.webp "9-Benzyl-2,9-diazaspiro[5.5]undecane dihydrochloride structure")
9-Benzyl-2,9-diazaspiro[5.5]undecane dihydrochloride
CAS Number:
1198286-24-6
Molecular Formula:
C16H26Cl2N2
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