2-Hydroxy-N-{3-[3-(1-piperidinylmethyl)phenoxy]propyl}acetamide | CAS No. 78273-80-0

2-Hydroxy-N-{3-[3-(1-piperidinylmethyl)phenoxy]propyl}acetamide

Basic Information

CAS Number

78273-80-0

Molecular Formula

C17H26N2O3

Molecular Weight

306.41 g/mol

AD

Basic Physical Properties

C1CCN(CC1)CC2=CC(=CC=C2)OCCCNC(=O)CO

InChI

InChI=1S/C17H26N2O3/c20-14-17(21)18-8-5-11-22-16-7-4-6-15(12-16)13-19-9-2-1-3-10-19/h4,6-7,12,20H,1-3,5,8-11,13-14H2,(H,18,21)

InChIKey

BCCREUFCSIMJFS-UHFFFAOYSA-N

LogP

1.5499

Topological Polar Surface Area

61.8 Ų

Hydrogen Bond Donor/Acceptor

2 / 5

Complexity

319

Synonyms & References

English

  • Acetamide, 2-hydroxy-N-(3-(3-(1-piperidinylmethyl)phenoxy)propyl)-
  • 2-hydroxy-N-(3-{3-[(piperidin-1-yl)methyl]phenoxy}propyl)acetamide
  • BCCREUFCSIMJFS-UHFFFAOYSA-N
  • BCP13552
  • SR-01000944538
  • 2-hydroxy-N-[3-[3-(piperidin-1-ylmethyl)phenoxy]propyl]acetamide
  • MFCD00871807
  • Q415039
  • CS-0143056
  • SY293181
  • Desacetyl-tzu-0460
  • 78273-80-0
  • IV9VHT3YUM
  • N-[3-[3-(1-piperidinylmethyl)phenoxy]propyl]hydroxyacetamide
  • NS00005386
  • L012909
  • FT-0756141
  • 2-hydroxy-N-[3-[3-(1-piperidylmethyl)phenoxy]propyl]acetamide
  • UNII-IV9VHT3YUM
  • 2-hydroxy-N-(3-(3-(piperidin-1-ylmethyl)phenoxy)propyl)acetamide
  • HY-137941
  • D08494
  • Roxatidine [INN:BAN]
  • SR-01000944538-1
  • ROXATIDINE [INN]
  • DTXSID30228937
  • AKOS015896584
  • ROXATIDINE [WHO-DD]
  • Acetamide, 2-hydroxy-N-[3-[3-(1-piperidinylmethyl)phenoxy]propyl]-
  • Roxatidine (INN)
  • Roxit (TN)

MDL Number

MFCD00871807

Customs Code

2933399090

FAQ

What is 2-Hydroxy-N-{3-[3-(1-piperidinylmethyl)phenoxy]propyl}acetamide (CAS: 78273-80-0)?

2-Hydroxy-N-{3-[3-(1-piperidinylmethyl)phenoxy]propyl}acetamide is a chemical compound with the CAS number 78273-80-0. It is a white to off-white solid with a specific chemical structure that includes an acetamide group, a piperidinylmethyl moiety, and a phenoxy group attached to a propyl chain. This compound is water-soluble and has a molecular weight of approximately 382.46 g/mol.

What are the main uses of 2-Hydroxy-N-{3-[3-(1-piperidinylmethyl)phenoxy]propyl}acetamide (CAS: 78273-80-0)?

2-Hydroxy-N-{3-[3-(1-piperidinylmethyl)phenoxy]propyl}acetamide is primarily used as a pharmaceutical intermediate in the synthesis of active pharmaceutical ingredients (APIs). It finds applications in the development of anti-inflammatory and analgesic drugs. Additionally, it is used in the cosmetic industry for its potential skin benefits.

Is 2-Hydroxy-N-{3-[3-(1-piperidinylmethyl)phenoxy]propyl}acetamide (CAS: 78273-80-0) safe?

2-Hydroxy-N-{3-[3-(1-piperidinylmethyl)phenoxy]propyl}acetamide is generally considered safe for its intended industrial and pharmaceutical uses when handled with proper precautions. However, it should be stored away from direct sunlight and protected from moisture to minimize degradation. Users are advised to follow standard safety guidelines and wear appropriate personal protective equipment (PPE) during handling.

How should 2-Hydroxy-N-{3-[3-(1-piperidinylmethyl)phenoxy]propyl}acetamide (CAS: 78273-80-0) be stored?

2-Hydroxy-N-{3-[3-(1-piperidinylmethyl)phenoxy]propyl}acetamide should be stored in a tightly closed container in a cool, dry place, away from direct sunlight and heat sources. It should be kept at a temperature not exceeding 25°C. Proper ventilation should be maintained during handling to avoid inhalation of dust or fumes.

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