1-({[2-(Trimethylsilyl)ethoxy]carbonyl}oxy)-2,5-pyrrolidinedione

Basic Information

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CAS Number

78269-85-9

Molecular Formula

C10H17NO5Si

Molecular Weight

259.33 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Melting Point

98.0 to 102.0 deg-C

Boiling Point

308.6°C at 760 mmHg

Density

1.17±0.1 g/cm3 (20 ºC 760 Torr),

Flash Point

140.4°C

Refractive Index

1.479

Vapor Pressure

0.0±0.7 mmHg at 25°C

SMILES

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C[Si](C)(C)CCOC(=O)ON1C(=O)CCC1=O

InChI

InChI=1S/C10H17NO5Si/c1-17(2,3)7-6-15-10(14)16-11-8(12)4-5-9(11)13/h4-7H2,1-3H3

InChIKey

FLDNDAMSCINJDX-UHFFFAOYSA-N

LogP

1.5417999999999998

Topological Polar Surface Area

72.91 Å²

Hydrogen Bond Donor/Acceptor

0 / 6

Complexity

320

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Synonyms & References

English

2,5-Pyrrolidinedione, 1-[[[2-(trimethylsilyl)ethoxy]carbonyl]oxy]-
FLDNDAMSCINJDX-UHFFFAOYSA-N
N-(trimethylsilylethyloxycarbonyloxy)succinimide
SY036338
N-[2-(Trimethylsilyl)ethoxycarbonyloxy]succinimide
1-[2(Trimethylsilyl)ethoxycarbonyloxy]pyrrolidin-2,5-dione
TeocOSu
Teoc-OSu
EN300-7423933
1-[2-(Trimethylsilyl)ethoxycarbonyloxy]pyrrolidin-2,5-dione
2,5-Dioxopyrrolidin-1-yl (2-(trimethylsilyl)ethyl) carbonate
AKOS015840149
(2,5-dioxopyrrolidin-1-yl) 2-trimethylsilylethyl Carbonate
78269-85-9
C10H17NO5Si
1-({[2-(trimethylsilyl)ethoxy]carbonyl}oxy)pyrrolidine-2,5-dione
CS-W005141
1-(2-(TRIMETHYLSILYL)ETHOXYCARBONYLOXY)&
DTXSID10407561
SCHEMBL208184
T2591
1-[2-(trimethylsilyl)ethoxycarbonyloxy]pyrrolidine-2,5-dione
2,5-dioxopyrrolidin-1-yl 2-(trimethylsilyl)ethyl carbonate
2,5-Dioxopyrrolidin-1-yl(2-(trimethylsilyl)ethyl)carbonate
2,5-Dioxopyrrolidin-1-yl (2-(trimethylsilyl)-ethyl) carbonate
1-[2-(Trimethylsilyl)ethoxy-carbonyloxy]pyrrolidin-2,5-dione
MFCD02683467
carbonic acid 2,5-dioxo-pyrrolidin-1-yl ester 2-trimethylsilanyl-ethyl ester
AS-10140
(2,5-dioxopyrrolidin-1-yl) 2-trimethylsilylethyl carbonate
Carbonic acid,2,5-dioxo-1-pyrrolidinyl [2-(trimethylsilyl)ethyl] ester

MDL Number

MFCD02683467

Customs Code

2931900090

FAQ

What is 1-({[2-(Trimethylsilyl)ethoxy]carbonyl}oxy)-2,5-pyrrolidinedione (CAS: 78269-85-9)?

1-({[2-(Trimethylsilyl)ethoxy]carbonyl}oxy)-2,5-pyrrolidinedione is a cyclic diketone derivative. It is a colorless solid with a molecular formula of C13H23NO4. This compound is commonly used as a protective group in organic synthesis, particularly in the manipulation of amine functionalities.

What are the main uses of 1-({[2-(Trimethylsilyl)ethoxy]carbonyl}oxy)-2,5-pyrrolidinedione (CAS: 78269-85-9)?

1-({[2-(Trimethylsilyl)ethoxy]carbonyl}oxy)-2,5-pyrrolidinedione is primarily used as a protecting group in organic chemistry. It is extensively applied in the pharmaceutical industry for the synthesis of complex molecules and in research for the modification of amine groups to prevent unwanted side reactions.

Is 1-({[2-(Trimethylsilyl)ethoxy]carbonyl}oxy)-2,5-pyrrolidinedione (CAS: 78269-85-9) safe?

1-({[2-(Trimethylsilyl)ethoxy]carbonyl}oxy)-2,5-pyrrolidinedione is generally safe when handled with appropriate precautions. However, it should be used in a well-ventilated area to avoid inhalation and direct contact with skin and eyes. Protective equipment such as gloves and goggles should be worn during handling.

How should 1-({[2-(Trimethylsilyl)ethoxy]carbonyl}oxy)-2,5-pyrrolidinedione (CAS: 78269-85-9) be stored?

1-({[2-(Trimethylsilyl)ethoxy]carbonyl}oxy)-2,5-pyrrolidinedione should be stored in a cool, dry place away from direct sunlight and sources of heat. It should be kept in a tightly sealed container to prevent moisture absorption and degradation. Refrigeration is not typically required but can be considered for extended storage periods.