Telcagepant | CAS No. 781649-09-0

Telcagepant

Basic Information

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CAS Number

781649-09-0

Molecular Formula

C26H27F5N6O3

Molecular Weight

566.5 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Density

1.54

SMILES

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C1CC(C(=O)N(CC1C2=C(C(=CC=C2)F)F)CC(F)(F)F)NC(=O)N3CCC(CC3)N4C5=C(NC4=O)N=CC=C5

InChI

InChI=1S/C26H27F5N6O3/c27-18-4-1-3-17(21(18)28)15-6-7-19(23(38)36(13-15)14-26(29,30)31)33-24(39)35-11-8-16(9-12-35)37-20-5-2-10-32-22(20)34-25(37)40/h1-5,10,15-16,19H,6-9,11-14H2,(H,33,39)(H,32,34,40)/t15-,19-/m1/s1

InChIKey

CGDZXLJGHVKVIE-DNVCBOLYSA-N

LogP

3.6864000000000026

Topological Polar Surface Area

103.33 Å²

Hydrogen Bond Donor/Acceptor

2 / 9

Complexity

948

Synonyms & References

English

TELCAGEPANT [WHO-DD]
MK-0974
TELCAGEPANT [INN]
N-[(3R,6S)-6-(2,3-difluorophenyl)-2-oxo-1-(2,2,2-trifluoroethyl)azepan-3-yl]-4-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide
Telcagepant (USAN)
AKOS015900692
BCP07257
MS-30255
BDBM50224431
N7R
NS00071851
N-[(3R,6S)-6-(2,3-Difluorophenyl)hexahydro-2-oxo-1-(2,2,2-trifluoroethyl)-1H-azepin-3-yl]-4-(2,3-dihydro-2-oxo-1H-imidazo[4,5-b]pyridin-1-yl)-1-piperidinecarboxamide;Telcagepant
N-((3R,6S)-6-(2,3-difluorophenyl)-2-oxo-1-(2,2,2-trifluoroethyl)azepan-3-yl)-4-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide
TELCAGEPANT [MI]
MK 0974
SCHEMBL1198535
GTPL703
D42O649ALL
CHEMBL236593
MK0974
Q5675567
CS-0291
HY-32709
TELCAGEPANT [MART.]
MK 0974, Telcagepant
N-[(3R,6S)-6-(2,3-difluorophenyl)-2-oxo-1-(2,2,2-trifluoroethyl)azepan-3-yl]-4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide
DB12228
D09391
DTXSID50999410
N-((3R,6S)-6-(2,3-difluorophenyl)-2-oxo-1-(2,2,2-trifluoroethyl)hexahydro-1h-azepin-3- yl)-4-(2-oxo-2,3-dihydro-1H-imidazo(4,5-b)pyridin-1-yl)piperidine-1-carboxamide
3n7r

MDL Number

MFCD22741412

FAQ

What is Telcagepant (CAS: 781649-09-0)?

Telcagepant is a selective antagonist of the calcitonin gene-related peptide (CGRP) receptor. It is used for the acute treatment of migraine with or without aura in adults. Telcagepant has a chemical structure and belongs to the class of drugs known as CGRP receptor antagonists.

What are the main uses of Telcagepant (CAS: 781649-09-0)?

Telcagepant is primarily used for the acute treatment of migraine with or without aura in adults. It works by blocking the action of CGRP, a substance that can contribute to migraine pain. Telcagepant is available as an oral formulation and is taken by mouth.

Is Telcagepant (CAS: 781649-09-0) safe?

Telcagepant is generally considered safe when used as directed. However, like any medication, it can cause side effects such as nausea and dizziness. It is important to follow the prescribed dosage and consult a healthcare provider if any adverse reactions are experienced. Precautions include avoiding driving or operating machinery if dizziness occurs.

How should Telcagepant (CAS: 781649-09-0) be stored?

Telcagepant should be stored at room temperature, between 15°C and 30°C (59°F and 86°F). It should be kept in a tightly closed container to protect it from moisture and light. Avoid storing it in places with extreme temperatures or direct sunlight. Store out of reach of children and pets.