(1R,3R,4aS,7S,8S,8aS)-8-{2-[(2R,4R)-4-Hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl}-3,7-dimethyl-1,2,3,4,4a,7,8,8a-octahydro-1-naphthalenyl (2S)-2-methylbutanoate | CAS No. 77517-29-4

(1R,3R,4aS,7S,8S,8aS)-8-{2-[(2R,4R)-4-Hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl}-3,7-dimethyl-1,2,3,4,4a,7,8,8a-octahydro-1-naphthalenyl (2S)-2-methylbutanoate

Basic Information

CAS Number

77517-29-4

Molecular Formula

C24H38O5

Molecular Weight

406.56 g/mol

AD

Basic Physical Properties

CCC(C)C(=O)OC1CC(CC2C1C(C(C=C2)C)CCC3CC(CC(=O)O3)O)C

InChI

InChI=1S/C24H38O5/c1-5-15(3)24(27)29-21-11-14(2)10-17-7-6-16(4)20(23(17)21)9-8-19-12-18(25)13-22(26)28-19/h6-7,14-21,23,25H,5,8-13H2,1-4H3/t14-,15+,16+,17-,18-,19-,20+,21-,23+/m1/s1

InChIKey

IFIFFBWHLKGTMO-SXOWJBHNSA-N

LogP

4.275400000000004

Topological Polar Surface Area

72.83000000000001 Ų

Hydrogen Bond Donor/Acceptor

1 / 5

Complexity

614

Synonyms & References

English

  • 4a,5-Dihydromevinolin
  • Butanoic acid, 2-methyl-, 1,2,3,4,4a,7,8,8a-octahydro-3,7-dimethyl-8-(2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl)-1-naphthalenyl ester, (1S-(1alpha(R*),3alpha,4aalpha,7beta,8beta(2S*,4S*),8abeta))-
  • Dihydromevinolin
  • DTXSID00998716
  • UNII-W53N9X64FM
  • Lovastatin EP Impurity E
  • SCHEMBL5597812
  • W53N9X64FM
  • [(1S,3S,4aR,7S,8S,8aR)-8-[2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl]-3,7-dimethyl-1,2,3,4,4a,7,8,8a-octahydronaphthalen-1-yl] (2S)-2-methylbutanoate
  • 77517-29-4
  • Dihydro-lovastatin
  • Lovastatin Related Compound A
  • dihydromevinolin
  • 4a,5-Dihydro Lovastatin
  • (1S,3S,4aR,7S,8S,8aR)-8-{2-[(2R,4R)-4-Hydroxy-6-oxotetrahydro-2H- pyran-2-yl]ethyl}-3,7-dimethyl-1,2,3,4,4a,7,8,8a-octahydro-1-naph thalenyl (2S)-2-methylbutanoate
  • LOVASTATIN EP IMPURITY D
  • Dihydrolovastatin

FAQ

What is (1R,3R,4aS,7S,8S,8aS)-8-{2-[(2R,4R)-4-Hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl}-3,7-dimethyl-1,2,3,4,4a,7,8,8a-octahydro-1-naphthalenyl (2S)-2-methylbutanoate (CAS: 77517-29-4)?

This compound is a complex organic molecule with a specific stereochemistry and structure, commonly used in pharmaceuticals and research. It is derived from naphthalene and features a unique substitution pattern on the 8th position, with a methylbutanoate group attached to a hydroxycyclohexane ring.

What are the main uses of (1R,3R,4aS,7S,8S,8aS)-8-{2-[(2R,4R)-4-Hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl}-3,7-dimethyl-1,2,3,4,4a,7,8,8a-octahydro-1-naphthalenyl (2S)-2-methylbutanoate (CAS: 77517-29-4)?

This compound is primarily used in the pharmaceutical industry for its potential as a drug intermediate. In research, it is utilized for its unique chemical properties and structural features, often in synthetic chemistry and material science applications.

Is (1R,3R,4aS,7S,8S,8aS)-8-{2-[(2R,4R)-4-Hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl}-3,7-dimethyl-1,2,3,4,4a,7,8,8a-octahydro-1-naphthalenyl (2S)-2-methylbutanoate (CAS: 77517-29-4) safe?

This compound is generally safe when handled under appropriate conditions and with proper protective measures. Users should follow standard laboratory safety protocols, including wearing appropriate personal protective equipment and working in a well-ventilated area.

How should (1R,3R,4aS,7S,8S,8aS)-8-{2-[(2R,4R)-4-Hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl}-3,7-dimethyl-1,2,3,4,4a,7,8,8a-octahydro-1-naphthalenyl (2S)-2-methylbutanoate (CAS: 77517-29-4) be stored?

This compound should be stored in a cool, dry place away from direct sunlight and moisture. It should be kept in a tightly sealed container to prevent degradation. Optimal storage temperature is below 25°C (77°F), and it should be protected from high humidity to maintain its stability.

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