1-(4-Fluoro-3-nitrophenyl)methanamine

Basic Information

View in Editor

CAS Number

771581-73-8

Molecular Formula

C7H7FN2O2

Molecular Weight

170.14 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Electronic Chemicals Semiconductor Materials Etchants

Basic Physical Properties

Boiling Point

311.2±27.0 °C at 760 mmHg

Density

1.4±0.1 g/cm3

Flash Point

142.0±23.7 °C

Vapor Pressure

0.0±0.7 mmHg at 25°C

SMILES

View in Editor

C1=CC(=C(C=C1CN)[N+](=O)[O-])F

InChI

InChI=1S/C7H7FN2O2/c8-6-2-1-5(4-9)3-7(6)10(11)12/h1-3H,4,9H2

InChIKey

UALXEVNNBBBYCG-UHFFFAOYSA-N

LogP

2.41610

Complexity

171

Synonyms & References

English

CS-0455571
4-Fluoro-3-nitrobenzylamine
771581-73-8
4-Fluoro-3-nitro-benzylamine
UALXEVNNBBBYCG-UHFFFAOYSA-N
4-Fluoro-3-nitrophenyl) methanamine
FT-0746835
SB38687
A865339
EN300-1847567
N12600
2-(4-CHLORO-2-METHYLPHENOXY)ACETICACIDHYDRAZIDE
MFCD06212995
(4-FLUORO-3-NITROPHENYL)METHANAMINE
1-(4-Fluoro-3-nitrophenyl)methanamine
DTXSID90594064
AKOS006295821
SCHEMBL7615803
(4-FLUORO-3-NITROPHENYL) METHANAMINE
4-FLUORO-3-NITRO-BENZYLAMINE,
S01-0764

MDL Number

MFCD06212995

FAQ

What are the physical and chemical properties of 1-(4-Fluoro-3-nitrophenyl)methanamine (CAS: 771581-73-8)?

1-(4-Fluoro-3-nitrophenyl)methanamine (CAS: 771581-73-8) is a crystalline compound with a molecular weight of approximately 214.07 g/mol. It is slightly soluble in water and more soluble in organic solvents like ethanol and acetone. The compound shows low reactivity under normal conditions but can be sensitive to oxidizing agents due to its nitro and fluoro substituents. It exhibits acidic behavior due to the nitro group.

How is 1-(4-Fluoro-3-nitrophenyl)methanamine (CAS: 771581-73-8) typically synthesized?

1-(4-Fluoro-3-nitrophenyl)methanamine can be synthesized by coupling 4-fluoro-3-nitrobenzoic acid with methylamine. The synthesis involves esterification of the carboxylic acid group followed by nucleophilic substitution with methylamine. The reaction is typically conducted under mild conditions with appropriate solvents and catalysts to ensure high selectivity and yield. Common solvents include acetonitrile or dichloromethane.

What industries use 1-(4-Fluoro-3-nitrophenyl)methanamine (CAS: 771581-73-8)?

1-(4-Fluoro-3-nitrophenyl)methanamine (CAS: 771581-73-8) is used in the pharmaceutical industry for the synthesis of certain drugs. It also finds applications in the polymer industry for the development of advanced materials, and in the chemical sensor industry for detecting specific analytes. Its ability to form stable complexes with metal ions makes it useful in various analytical applications.

What precautions should be taken when handling 1-(4-Fluoro-3-nitrophenyl)methanamine (CAS: 771581-73-8)?

When handling 1-(4-Fluoro-3-nitrophenyl)methanamine (CAS: 771581-73-8), it is important to wear appropriate personal protective equipment (PPE), including gloves, safety goggles, and lab coat. The compound should be handled in a fume hood to minimize inhalation risks. Spills should be cleaned up using appropriate absorbent materials and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling instructions and emergency procedures.