6-ethoxypyridin-2-amine

Basic Information

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CAS Number

768-42-3

Molecular Formula

C7H10N2O

Molecular Weight

138.17 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

SMILES

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CCOC1=CC=CC(=N1)N

InChI

InChI=1S/C7H10N2O/c1-2-10-7-5-3-4-6(8)9-7/h3-5H,2H2,1H3,(H2,8,9)

InChIKey

VRZIITVWIJSXOA-UHFFFAOYSA-N

LogP

1.0624999999999998

Topological Polar Surface Area

48.14 Å²

Hydrogen Bond Donor/Acceptor

2 / 3

Complexity

97.6

Synonyms & References

English

SY065666
6-Ethoxy-2-pyridinamine #
6-ETHOXY-PYRIDIN-2-YLAMINE
Pyridin-2-amine, 6-ethoxy-
DTXSID70343017
2-Amino-6-ethoxypyridine
6-amino-2-ethoxypyridine
A9735
6-Ethoxy-2-pyridinamine
MFCD00235129
SCHEMBL107591
EN300-89876
CS-0061653
J-518686
AC-13283
AB05302
768-42-3
6-ethoxypyridin-2-amine
AKOS012899704
6-ethoxypyridin-2-ylamine
FT-0687911
Z1139188017
6-amino-2-ethoxy pyridine
6-Ethoxy-pyridin-2-ylamine
2-Amino-6-ethoxy-pyridin
2-Ethoxy-6-amino-pyridin
6-Aethoxy-[2]pyridylamin
6-ethoxy-2-pyridylamine

MDL Number

MFCD00235129

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 6-ethoxypyridin-2-amine (CAS: 768-42-3)?

6-Ethoxypyridin-2-amine (CAS: 768-42-3) is a white to off-white crystalline solid with a molecular weight of approximately 147.17 g/mol. It is slightly soluble in water but soluble in common organic solvents such as ethanol and acetone. It is moderately reactive and can undergo nucleophilic substitution reactions. This compound is also known for its basic properties, making it amenable to acid-base interactions.

How is 6-ethoxypyridin-2-amine (CAS: 768-42-3) typically synthesized?

6-Ethoxypyridin-2-amine (CAS: 768-42-3) can be synthesized through amination of 2-chloropyridine with ethylamine in the presence of a base such as sodium carbonate. The reaction typically yields a high percentage of the desired product with good selectivity. Catalysts like palladium or copper may enhance the reaction rate and yield.

What industries use 6-ethoxypyridin-2-amine (CAS: 768-42-3)?

6-Ethoxypyridin-2-amine (CAS: 768-42-3) is primarily used in the pharmaceutical industry for the synthesis of various drug candidates. It also finds applications in the polymer industry for the preparation of functional polymers and in the semiconductor industry for the production of organic thin-film transistors. Additionally, it is used in the development of sensors for detecting specific chemical species.

What precautions should be taken when handling 6-ethoxypyridin-2-amine (CAS: 768-42-3)?

When handling 6-ethoxypyridin-2-amine (CAS: 768-42-3), it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat to protect against skin contact and eye exposure. The compound should be stored in a well-ventilated area and away from open flames and oxidizers. In case of a spill, use appropriate absorbent materials and dispose of them according to local regulations. Refer to the Material Safety Data Sheet (MSDS) for detailed safety information.