2,2,3,3-Tetrafluoropropanoic acid

Basic Information

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CAS Number

756-09-2

Molecular Formula

C3H2F4O2

Molecular Weight

146.04 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Fine Chemicals Specialty Chemicals UV Stabilizers

Electronic Chemicals Semiconductor Materials Etchants

Water Treatment Chemicals Coagulants and Flocculants Inorganic Coagulants

Water Treatment Chemicals Disinfectants Chlorine Compounds

Basic Physical Properties

Boiling Point

133°C

Density

1,563 g/cm3

Water Solubility

Sparingly soluble in water.

Flash Point

133-134°C

Refractive Index

1.321

Vapor Pressure

3.5±0.5 mmHg at 25°C

SMILES

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C(C(C(=O)O)(F)F)(F)F

InChI

InChI=1S/C3H2F4O2/c4-1(5)3(6,7)2(8)9/h1H,(H,8,9)

InChIKey

PXRROZVNOOEPPZ-UHFFFAOYSA-N

LogP

0.9714000000000003

Topological Polar Surface Area

37.3 Å²

Hydrogen Bond Donor/Acceptor

1 / 2

Complexity

121

Safety Information

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Hazard Statement

H290 May be corrosive to metals
Corrosive to Metals

H314 Causes severe skin burns and eye damage
Skin corrosion/irritation

Hazard Class

Class 8 Class 8

Synonyms & References

English

756-09-2
PXRROZVNOOEPPZ-UHFFFAOYSA-
CHEBI:82013
Propanoic acid, 2,2,3,3-tetrafluoro-
T1777
tetrafluoropropionic acid
2,2,3,3-Tetrafluoropropionic acid;3H-Tetrafluoropropionic acid
BS-42255
2,2,3,3-Tetrafluoropropionic acid
Flupropanate [ISO]
InChI=1/C3H2F4O2/c4-1(5)3(6,7)2(8)9/h1H,(H,8,9)
3H-Tetrafluoropropionic acid
AKOS002662653
376KS3J2Q6
Flupropanate
UNII-376KS3J2Q6
C18854
DTXSID7058177
Q27155689
FT-0609052
EN300-96639
SCHEMBL128482
3h-tetrafluoropropanoic acid
AC9459
2,2,3,3-tetrafluoropropanoic acid
F0001-1912
NS00019239
SY047513
MFCD00054686
EINECS 212-049-7
3H-tetrafluoropropionic acid

MDL Number

MFCD00054686

FAQ

What are the physical and chemical properties of 2,2,3,3-Tetrafluoropropanoic acid (CAS: 756-09-2)?

2,2,3,3-Tetrafluoropropanoic acid is a colorless, crystalline solid with a high melting point. Its molecular weight is approximately 170.99 g/mol. It is poorly soluble in water but soluble in organic solvents. Reactively, it is a carboxylic acid and can undergo typical carboxylic acid transformations such as esterification and reaction with bases. It is stable under normal conditions but sensitive to strong bases and reducing agents.

How is 2,2,3,3-Tetrafluoropropanoic acid (CAS: 756-09-2) typically synthesized?

2,2,3,3-Tetrafluoropropanoic acid is typically synthesized through the bromination of 2,2,3,3-tetrafluoropropane followed by hydrolysis. The reaction proceeds via a bromonium ion intermediate, which is then hydrolyzed to form the carboxylic acid. This process requires careful control of temperature and reaction conditions to achieve high selectivity and yield.

What industries use 2,2,3,3-Tetrafluoropropanoic acid (CAS: 756-09-2)?

2,2,3,3-Tetrafluoropropanoic acid is used in the pharmaceutical industry for the synthesis of intermediates and functional groups in drug molecules. It is also utilized in the polymer industry to modify the properties of polymers, in sensor technology for detecting specific analytes, and in semiconductor applications as a cleaning agent for surfaces.

What precautions should be taken when handling 2,2,3,3-Tetrafluoropropanoic acid (CAS: 756-09-2)?

When handling 2,2,3,3-Tetrafluoropropanoic acid, it is important to wear appropriate personal protective equipment (PPE) including gloves, safety goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to avoid inhalation. Spills should be handled carefully using appropriate absorbents, and the area should be cleaned thoroughly. Always refer to the Safety Data Sheet (SDS) for specific guidelines and emergency procedures.