2-Chloro-1,1,1-trimethoxyethane

Basic Information

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CAS Number

74974-54-2

Molecular Formula

C5H11ClO3

Molecular Weight

154.59 g/mol

Basic Physical Properties

Boiling Point

138 °C

Density

1.147 g/mL at 25 °C

Refractive Index

n20/D 1.425(lit.)

SMILES

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COC(CCl)(OC)OC

InChI

InChI=1S/C5H11ClO3/c1-7-5(4-6,8-2)9-3/h4H2,1-3H3

InChIKey

NPEIUNVTLXEOLT-UHFFFAOYSA-N

LogP

0.8182

Topological Polar Surface Area

27.69 Å²

Hydrogen Bond Donor/Acceptor

0 / 3

Complexity

64.3

Safety Information

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GHS Hazard Pictograms

H226

Hazard Statement

H226 Flammable liquid and vapor
Flammable liquids

Hazard Class

Class 3 Class 3

Synonyms & References

English

2-Chloro-1,1,1-trimethoxyethane
1,1,1-trimethoxy-2-chloroethane
TMOCA
TRIMETHYL CHLORO-ORTHOACETATE
2-Chloro-1,1,1-trimethoxyethane,Trimethyl chloro-orthoacetate
1-chloro-2,2,2-trimethoxyethane
2-chloro-1,1,1-trimethoxy-ethane
Ethane, 2-chloro-1,1,1-trimethoxy-
trimethoxy chloroethane
C5H11ClO3
KSC496I9T
NPEIUNVTLXEOLT-UHFFFAOYSA-N
2-chloro-1,1,1 trimethoxyethane
2-chloro-1,1,1-trimethoxy ethane
1-chloro-2,2,2- trimethoxyethane
BCP11323
2-chloro-1,1,1-trime

MDL Number

MFCD00216629

Customs Code

2909199090

FAQ

What is 2-Chloro-1,1,1-trimethoxyethane (CAS: 74974-54-2)?

2-Chloro-1,1,1-trimethoxyethane (CAS: 74974-54-2) is an organochlorine ether with the chemical formula C5H11ClO3. It is a clear, colorless liquid with a sweet, ether-like odor, characterized by its chloro and methoxy functional groups. This compound exhibits moderate solubility in organic solvents and is commonly used in chemical synthesis due to its reactivity and stability under controlled conditions.

What are the main uses of 2-Chloro-1,1,1-trimethoxyethane (CAS: 74974-54-2)?

2-Chloro-1,1,1-trimethoxyethane (CAS: 74974-54-2) is primarily used as an intermediate in pharmaceutical and industrial applications. It plays a role in the synthesis of organic compounds, including agrochemicals and specialty chemicals. In research, it serves as a reagent for modifying functional groups. Its versatility makes it valuable in creating derivatives for drug development and material science.

Is 2-Chloro-1,1,1-trimethoxyethane (CAS: 74974-54-2) safe?

2-Chloro-1,1,1-trimethoxyethane (CAS: 74974-54-2) requires caution due to its potential toxicity. It may cause skin and eye irritation, and inhalation can be harmful. Safety guidelines recommend handling in well-ventilated areas, using protective gloves and goggles, and adhering to OSHA and REACH standards. Always follow proper safety protocols to minimize exposure risks.

How should 2-Chloro-1,1,1-trimethoxyethane (CAS: 74974-54-2) be stored?

2-Chloro-1,1,1-trimethoxyethane (CAS: 74974-54-2) should be stored in a cool, dry, and dark place, ideally below 25°C. Keep it in a sealed, airtight container to prevent evaporation and contamination. Avoid exposure to moisture, air, and direct sunlight. Store in a well-ventilated area, away from incompatible materials, to ensure stability and safety.