2-Methyl 1-(2-methyl-2-propanyl) (2R)-1,2-pyrrolidinedicarboxylate

Basic Information

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CAS Number

73323-65-6

Molecular Formula

C11H19NO4

Molecular Weight

229.28 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Boiling Point

288.6℃ at 760 mmHg

Solubility

Soluble in DMSO.

Refractive Index

1.4510-1.4550

SMILES

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CC(C)(C)OC(=O)N1CCCC1C(=O)OC

InChI

InChI=1S/C11H19NO4/c1-11(2,3)16-10(14)12-7-5-6-8(12)9(13)15-4/h8H,5-7H2,1-4H3/t8-/m1/s1

InChIKey

WVDGSSCWFMSRHN-MRVPVSSYSA-N

LogP

1.5589

Topological Polar Surface Area

55.84 Å²

Hydrogen Bond Donor/Acceptor

0 / 5

Complexity

282

Safety Information

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Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

DE-0044
EN300-196436
WVDGSSCWFMSRHN-MRVPVSSYSA-N
BOC-(R)-proline methyl ester
O1-tert-butyl O2-methyl (2R)-pyrrolidine-1,2-dicarboxylate
A26496
SCHEMBL1486184
1-O-tert-butyl 2-O-methyl (2R)-pyrrolidine-1,2-dicarboxylate
DTXSID40361581
N-Boc-D-proline methyl ester
MFCD00190828
Q-101837
(R)-1-tert-Butyl 2-methyl pyrrolidine-1,2-dicarboxylate
73323-65-6
Methyl (R)-1-(tert-butoxycarbonyl)pyrrolidine-2-carboxylate
CS-W019985
AKOS005258752
boc-d-proline methyl ester
AM20100703
1-TERT-BUTYL 2-METHYL (2R)-PYRROLIDINE-1,2-DICARBOXYLATE
N-(tert-Butoxycarbonyl)-D-proline Methyl Ester
AC-2245
1-(tert-butyl) 2-methyl (R)-pyrrolidine-1,2-dicarboxylate
B4787
Boc-D-Pro-Ome
N-tert-Butoxycarbonyl-D-Proline methyl ester
1-tert-Butyl 2-methyl (2R)-pyrrolidine-1,2-dicarboxylate
Boc-D-proline methyl ester
(2R)-N-(tert-butoxycarbonyl)proline
(R)-N-tert-butoxycarbonylproline methyl ester
1-(tert-butoxycarbonyl)-(R)-proline methyl ester

MDL Number

MFCD00190828

Customs Code

2933990090

FAQ

What are the physical and chemical properties of 2-Methyl 1-(2-methyl-2-propanyl) (2R)-1,2-pyrrolidinedicarboxylate (CAS: 73323-65-6)?

2-Methyl 1-(2-methyl-2-propanyl) (2R)-1,2-pyrrolidinedicarboxylate is a crystalline solid with a molecular weight of approximately 268.36 g/mol. It has a solubility of about 0.1 g/100 mL in water. This compound is reactive under certain conditions and can undergo esterification and hydrogenation. It is stable under normal laboratory conditions but should be handled with care.

How is 2-Methyl 1-(2-methyl-2-propanyl) (2R)-1,2-pyrrolidinedicarboxylate (CAS: 73323-65-6) typically synthesized?

2-Methyl 1-(2-methyl-2-propanyl) (2R)-1,2-pyrrolidinedicarboxylate is typically synthesized via a multi-step process involving the conversion of pyrrolidines to the corresponding carboxylic acids, followed by esterification. The synthesis often employs catalytic hydrogenation and esterification reactions with high selectivity and yield. Common catalysts include palladium-based catalysts.

What industries use 2-Methyl 1-(2-methyl-2-propanyl) (2R)-1,2-pyrrolidinedicarboxylate (CAS: 73323-65-6)?

2-Methyl 1-(2-methyl-2-propanyl) (2R)-1,2-pyrrolidinedicarboxylate is used in the pharmaceutical industry for the synthesis of drugs, in polymer chemistry as a monomer, and in the electronics sector for sensor development. Its versatile chemical properties make it valuable in these industries for its reactivity and stability.

What precautions should be taken when handling 2-Methyl 1-(2-methyl-2-propanyl) (2R)-1,2-pyrrolidinedicarboxylate (CAS: 73323-65-6)?

When handling 2-Methyl 1-(2-methyl-2-propanyl) (2R)-1,2-pyrrolidinedicarboxylate, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and lab coat. This compound should be handled in a well-ventilated area or a fume hood. In case of a spill, immediately use appropriate spill cleanup materials. Always refer to the Safety Data Sheet (SDS) for detailed safety information.