Oxacillin sodium monohydrate

Basic Information

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CAS Number

7240-38-2

Molecular Formula

C19H20N3NaO6S

Molecular Weight

441.4 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Melting Point

188°C(dec.)

Boiling Point

687℃

Water Solubility

Freely soluble in water

Flash Point

>110°(230°F)

Refractive Index

205 ° (C=1, H2O)

Specific Rotation

D20 +201° (c = 1 in water)

SMILES

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CC1=C(C(=NO1)C2=CC=CC=C2)C(=O)NC3C4N(C3=O)C(C(S4)(C)C)C(=O)[O-].O.[Na+]

InChI

InChI=1S/C19H19N3O5S.Na.H2O/c1-9-11(12(21-27-9)10-7-5-4-6-8-10)15(23)20-13-16(24)22-14(18(25)26)19(2,3)28-17(13)22;;/h4-8,13-14,17H,1-3H3,(H,20,23)(H,25,26);;1H2/q;+1;/p-1/t13-,14+,17-;;/m1../s1

InChIKey

ZVIYWUUZWWBNMB-VICXVTCVSA-M

LogP

0.99210

Complexity

687

Safety Information

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Toxicity

LD50 orally in rats: >8000 mg/kg (Goldenthal)

Synonyms & References

English

Monosodium (2S,5R,6R)-3,3-dimethyl-6-(5-methyl-3-phenyl-4-isoxazolecarboxamido)-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate monohydrate
SCHEMBL720235
Prostaphlin
s2563
Oxacillin for peak identification, European Pharmacopoeia (EP) Reference Standard
NSC-757253
CHEBI:7810
Micropenin
O-4950
NSC 757253
oxacillin sodium monohydrate
OXACILLIN SODIUM [USAN]
sodium 6beta-(5-methyl-3-phenylisoxazol-4-yl)penicillanate hydrate
CCG-269136
Oxacillin sodium [USAN:USP:JAN]
OXACILLIN SODIUM [USP-RS]
Oxacillin sodium salt monohydrate
CHEMBL3989567
1173-88-2
Sodium oxacillin monohydrate
D00929
OXACILLIN SODIUM [VANDF]
Oxacillin sodium salt monohydrate, Antibiotic for Culture Media Use Only
Oxacillin (sodium monohydrate)
Oxacillin sodium salt monohydrate, VETRANAL(TM), analytical standard
Monosodium (2S,5R,6R)-3,3-dimethyl-6-(5-methyl-3-phenyl-4-isoxazolecarboxamido)-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylate monohydrate
OXACILLIN SODIUM [USP MONOGRAPH]
sodium(2S,5R,6R)-3,3-dimethyl-6-(5-methyl-3-phenylisoxazole-4-carboxamido)-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylatehydrate
SQ 16,423
Q27107594
sodium (2S,5R,6R)-3,3-dimethyl-6-(5-methyl-3-phenylisoxazole-4-carboxamido)-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate hydrate

MDL Number

MFCD00056864

Customs Code

3004101900

FAQ

What is Oxacillin sodium monohydrate (CAS: 7240-38-2)?

Oxacillin sodium monohydrate (CAS: 7240-38-2) is a semi-synthetic penicillin antibiotic used to treat bacterial infections. It has the chemical formula C16H18N2O5S2·H2O and exists as a white crystalline powder. It is soluble in water and has a molecular weight of 414.5 g/mol. Known for its stability and effectiveness against penicillinase-producing bacteria, it is commonly prescribed for respiratory and skin infections.

What are the main uses of Oxacillin sodium monohydrate (CAS: 7240-38-2)?

Oxacillin sodium monohydrate (CAS: 7240-38-2) is primarily used in pharmaceuticals to combat bacterial infections caused by Gram-positive pathogens, including Staphylococcus species. It is effective against penicillinase-producing strains and is prescribed for conditions such as pneumonia, wound infections, and sepsis. Its application also extends to veterinary medicine and research for antibiotic development.

Is Oxacillin sodium monohydrate (CAS: 7240-38-2) safe?

Oxacillin sodium monohydrate (CAS: 7240-38-2) is considered safe when used as directed, but it may cause side effects like gastrointestinal upset or allergic reactions. Proper handling with gloves and eye protection is recommended to minimize exposure. Safety standards ensure it meets pharmaceutical-grade quality, and adherence to prescribed dosages reduces risks. Always consult healthcare professionals for safe usage.

How should Oxacillin sodium monohydrate (CAS: 7240-38-2) be stored?

Oxacillin sodium monohydrate (CAS: 7240-38-2) should be stored in a cool, dry place at 2-8°C (36-46°F) to maintain stability. Protect from light and moisture by using airtight, moisture-proof containers. Avoid exposure to incompatible substances and ensure proper labeling. Storage conditions prevent degradation and ensure efficacy until the expiry date.