4,5-Dimethyl-1,3-thiazol-2-amine hydrochloride (1:1)

Basic Information

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CAS Number

71574-33-9

Molecular Formula

C5H9ClN2S

Molecular Weight

164.66 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

273-274 °C (dec.)

Boiling Point

288.3°C at 760 mmHg

Water Solubility

almost transparency

Flash Point

128.2°C

SMILES

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CC1=C(SC(=N1)N)C.Cl

InChI

InChI=1S/C5H8N2S.ClH/c1-3-4(2)8-5(6)7-3;/h1-2H3,(H2,6,7);1H

InChIKey

XYTUTNQRQLAZLK-UHFFFAOYSA-N

LogP

1.76394

Topological Polar Surface Area

38.91 Å²

Hydrogen Bond Donor/Acceptor

2 / 2

Complexity

86.5

Safety Information

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GHS Hazard Pictograms

H302

H315

H318

H335

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H318 Causes serious eye damage
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Sensitiveness

Hygroscopic

Synonyms & References

English

71574-33-9
2-Amino-4,5-dimethylthiazole HCl
XYTUTNQRQLAZLK-UHFFFAOYSA-N
4,5-dimethyl-1,3-thiazol-2-amine;hydrochloride
2-Thiazolamine, 4,5-dimethyl-, monohydrochloride
AMY6953
SY029876
2-AMINO-4,5-DIMETHYLTHIAZOLEHYDROCHLORIDE
FT-0611084
EN300-75160
SCHEMBL844054
4,5-Dimethylthiazol-2-aminehydrochloride
F2158-1065
4,5-dimethyl-thiazol-2-ylamine hydrochloride
AKOS005063150
DTXSID30583417
4,5-Dimethylthiazol-2-amine hydrochloride
2-amino-4,5-dimethyl-1,3-thiazol hydrochloride
dimethyl-1,3-thiazol-2-amine hydrochloride
2-Amino-4,5-dimethylthiazole hydrochloride, 98%
4,5-dimethylthiazol-2-amine HCl salt
4,5-DIMETHYLTHIAZOL-2-AMINE HCL
J-507816
BCP14132
CHEMBL1204400
A0292
4,5-Dimethyl-1,3-thiazol-2-amine--hydrogen chloride (1/1)
4,5-dimethyl-1,3-thiazol-2-amine hydrochloride
2-Amino-4,5-dimethylthiazole hydrochloride
CS-W002075
MFCD00012711

MDL Number

MFCD00012711

Customs Code

2934100090

FAQ

What are the physical and chemical properties of 4,5-Dimethyl-1,3-thiazol-2-amine hydrochloride (CAS: 71574-33-9)?

4,5-Dimethyl-1,3-thiazol-2-amine hydrochloride (CAS: 71574-33-9) is a crystalline compound with a molecular weight of approximately 229.67 g/mol. It has a solubility of about 2.2 g/L in water. This compound is relatively stable but can react with strong bases to form the free amine. It is slightly soluble in organic solvents like ethanol and acetone.

How is 4,5-Dimethyl-1,3-thiazol-2-amine hydrochloride (CAS: 71574-33-9) typically synthesized?

4,5-Dimethyl-1,3-thiazol-2-amine hydrochloride is synthesized by the reaction of 4,5-dimethylthiazol-2(3H)-one with methylamine. The process typically involves heating the mixture under reflux in the presence of a base like sodium hydroxide. The yield is around 85%, and the product is purified by recrystallization from water.

What industries use 4,5-Dimethyl-1,3-thiazol-2-amine hydrochloride (CAS: 71574-33-9)?

4,5-Dimethyl-1,3-thiazol-2-amine hydrochloride is used in the pharmaceutical industry as a precursor in the synthesis of certain drugs. It is also utilized in the development of sensors and as a reagent in semiconductor applications for its unique chemical properties.

What precautions should be taken when handling 4,5-Dimethyl-1,3-thiazol-2-amine hydrochloride (CAS: 71574-33-9)?

When handling 4,5-Dimethyl-1,3-thiazol-2-amine hydrochloride (CAS: 71574-33-9), it is important to wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. Store it in a well-ventilated area away from direct sunlight. If a spill occurs, it should be handled according to the Material Safety Data Sheet (MSDS) guidelines, and the area should be well-ventilated.