Saxagliptin Hydrochloride

Basic Information

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CAS Number

709031-78-7

Molecular Formula

C18H26ClN3O2

Molecular Weight

351.87 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Nitriles

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

SMILES

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C1C2CC2N(C1C#N)C(=O)C(C34CC5CC(C3)CC(C5)(C4)O)N.Cl

InChI

InChI=1S/C18H25N3O2.ClH/c19-8-13-2-12-3-14(12)21(13)16(22)15(20)17-4-10-1-11(5-17)7-18(23,6-10)9-17;/h10-15,23H,1-7,9,20H2;1H/t10?,11?,12-,13+,14+,15-,17?,18?;/m1./s1

InChIKey

TUAZNHHHYVBVBR-NHKADLRUSA-N

LogP

2.59818

Complexity

609

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

709031-78-7
CS-0006342
SAXAGLIPTIN HYDROCHLORIDE COMPONENT OF QTERN
SCHEMBL15152103
QTERNMET XR COMPONENT SAXAGLIPTIN HYDROCHLORIDE
TUAZNHHHYVBVBR-NHKADLRUSA-N
QTERN COMPONENT SAXAGLIPTIN HYDROCHLORIDE
SAXAGLIPTIN HYDROCHLORIDE COMPONENT OF KOMBIGLYZE
(1S,3S,5S)-2-[(2S)-2-amino-2-(3-hydroxy-1-adamantyl)acetyl]-2-azabicyclo[3.1.0]hexane-3-carbonitrile;hydrochloride
Saxagliptin hydrochloride
HY-16448
Saxagliptin (hydrochloride)
(1S,3S,5S)-2-[(2S)-Amino(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)acetyl]-2-azabicyclo[3.1.0]hexane-3-carbonitrile hydrochloride
2-Azabicyclo[3.1.0]hexane-3-carbonitrile,2-[(2S)-amino(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)acetyl]-,monohydrochloride, (1S,3S,5S)-
DS-8019
D10262
Onglyza (TN)
(1S,3S,5S)-2-((2S)-2-Amino-2-(3-hydroxyadamantan-1-yl)acetyl)-2-azabicyclo[3.1.0]hexane-3-carbonitrile hydrochloride
KOMBIGLYZE COMPONENT SAXAGLIPTIN HYDROCHLORIDE
CHEMBL1201743
SAXAGLIPTIN HYDROCHLORIDE (MART.)
SAXAGLIPTIN HYDROCHLORIDE [ORANGE BOOK]
(1S,3S,5S)-2-[(2S)-2-amino-2-(3-hydroxyadamantan-1-yl)acetyl]-2-azabicyclo[3.1.0]hexane-3-carbonitrile hydrochloride
Onglyza
2-Azabicyclo[3.1.0]hexane-3-carbonitrile, 2-[(2S)-2-amino-2-(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)acetyl]-, hydrochloride (1:1), (1S,3S,5S)-; 2-Azabicyclo[3.1.0]hexane-3-carbonitrile, 2-[(2S)-amino(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)acetyl]-, monohydrochloride, (1S,3S,5S)- (9CI); Saxagliptin hydrochloride
Saxagliptin HCl
UNII-Z8J84YIX6L
SAXAGLIPTIN HYDROCHLORIDE [WHO-DD]
SAXAGLIPTIN HYDROCHLORIDE [MART.]
DTXSID50991191
Q27295146

MDL Number

MFCD22572334

FAQ

What is Saxagliptin Hydrochloride (CAS: 709031-78-7)?

Saxagliptin Hydrochloride is a dipeptidyl peptidase-4 (DPP-4) inhibitor used in the management of type 2 diabetes. It is a white to off-white crystalline powder with a molecular formula of C16H17FN4O3·HCl and a molecular weight of approximately 357.8 g/mol.

What are the main uses of Saxagliptin Hydrochloride (CAS: 709031-78-7)?

Saxagliptin Hydrochloride is primarily used in the treatment of type 2 diabetes mellitus as an adjunct to diet and exercise to improve glycemic control. It is also used in combination with metformin or a thiazolidinedione.

Is Saxagliptin Hydrochloride (CAS: 709031-78-7) safe?

Saxagliptin Hydrochloride is generally considered safe when used as directed for the treatment of type 2 diabetes. However, it should be used with caution in patients with a history of cardiovascular disease, and careful monitoring is recommended. Always follow the instructions provided by healthcare professionals.

How should Saxagliptin Hydrochloride (CAS: 709031-78-7) be stored?

Saxagliptin Hydrochloride should be stored in a cool, dry place, protected from light and moisture. Store at a temperature not exceeding 25°C (77°F). Keep the container tightly closed to prevent moisture absorption.